Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Sep 20;9:934113. doi: 10.3389/fnut.2022.934113

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 Zhang, Xing, Wang, Tang, Wang and Gao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Potential targets in improvement of mitochondria function induced by imbalanced gut microbiota to attenuate NAFLD. Treatment strategy target to mitochondria had been explored. For example, application with sodium butyrate (NaB) can significantly enhance mitochondrial DNA content in HepG2 cell and increase the membrane potential function and the content of mitochondria to ameliorate its impaired dysfunction. NaB can elevate the activity of SOD and GPX and deplete the levels of prooxidative NOX2, ROS, and MDA; XOS enhanced the level of complex I and promote oxidative phosphorylation to improve mitochondrial respiratory capacity and evaluate the production of ATP; VVYP can decrease fragmentation of vacuolate and swollen mitochondria and improve the lipid metabolism.