Table 1.

To summarize the mechanism of IL-17 in different diseases

Disease	Mechanism	Refs
Aortic dissection	Reduced endothelial progenitor cells partly related to upregulated IL-6/IL-17 through DiI-acLDL/lectin and CD34+KDR+ cells	[161]
Cardiovascular diseases with (dyslipidemia, hypertension and diabetes mellitus)	Enhancement of IL-17 /IFN-γ production of CD4+28nullNKG2D+ T cells	[162]
Type 2 Diabetes Mellitus	IL-10/IL-17 correlated negatively with BMI or metabolic index	[163]
Preeclampsia	Mediated placental ischaemia and oxidative stress though AT1-AA production	[164, 165]
Idiopathic pulmonary arterial hypertension	TH17 cell immune polarization and IL-17A with disease severity or outcome associated conditions	[166, 167]
Systemic sclerosis	Activation of Th17 and Th1 cell responses	[168]
Schistosomiasis japonica	Activation of γδT cells and producing IL-17 against parasite eggs	[169]