Table 3.
Weighted ORs (95%CIs) of the association between α-klotho and oral health in stratified analyses.
| Characteristics | Moderate/severe periodontitis | Poor-rated oral health | Tooth loss | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Tertile 3 | Tertile 2 | Tertile 1 | P for trend | Tertile 3 | Tertile 2 | Tertile 1 | P for trend | Tertile 3 | Tertile 2 | Tertile 1 | P for trend | |
| Sex | ||||||||||||
| Female | Ref. | 1.24 (0.98, 1.58) |
1.19 (0.94, 1.51) |
0.24 | Ref. | 1.04 (0.79, 1.38) |
1.46 (1.10, 1.93) |
0.07 | Ref. | 1.60 (1.17, 2.19) |
1.57 (1.16, 2.13) |
<0.01 |
| Male | Ref. | 1.10 (0.83, 1.47) |
1.13 (0.85, 1.51) |
0.43 | Ref. | 1.11 (0.80, 1.55) |
1.15 (0.84, 1.59) |
0.14 | Ref. | 1.22 (0.82, 1.83) |
1.30 (0.88, 1.92) |
0.43 |
| Age | ||||||||||||
| <60 years | Ref. | 1.24 (0.99, 1.55) |
1.32 (1.06, 1.64) |
0.01 | Ref. | 1.24 (0.98, 1.57) |
1.25 (0.99, 1.58) |
0.12 | Ref. | 1.45 (1.02, 2.05) |
1.39 (0.91, 2.11) |
0.11 |
| ≥60 years | Ref. | 1.03 (0.69, 1.55) |
0.99 (0.78, 1.25) |
0.56 | Ref. | 0.93 (0.65, 1.34) |
1.20 (0.85, 1.69) |
0.78 | Ref. | 1.26 (0.88, 1.80) |
1.56 (1.15, 2.12) |
0.01 |
| Physical activity | ||||||||||||
| High/Moderate | Ref. | 1.12 (0.85, 1.47) |
1.16 (0.86, 1.57) |
0.29 | Ref. | 1.05 (0.74, 1.50) |
1.07 (0.72, 1.60) |
0.78 | Ref. | 1.28 (0.89, 1.84) |
1.29 (0.87, 1.92) |
0.17 |
| Low | Ref. | 1.13 (0.89, 1.45) |
1.21 (0.89, 1.62) |
0.24 | Ref. | 1.33 (1.01, 1.74) |
1.53 (1.16, 2.02) |
<0.01 | Ref. | 1.38 (0.97, 1.98) |
1.49 (1.05, 2.10) |
0.01 |
| BMI | ||||||||||||
| Underweight/Normal | Ref. | 1.09 (0.76, 1.56) |
1.00 (0.69, 1.43) |
0.96 | Ref. | 0.98 (0.69, 1.38) |
1.09 (0.74, 1.60) |
0.72 | Ref. | 0.89 (0.53, 1.48) |
0.95 (0.59, 1.54) |
0.81 |
| Overweight/Obese | Ref. | 1.24 (0.97, 1.59) |
1.24 (0.99, 1.56) |
0.10 | Ref. | 1.22 (0.99, 1.51) |
1.38 (1.10, 1.72) |
0.03 | Ref. | 1.38 (1.04, 1.84) |
1.55 (1.10, 2.16) |
0.02 |
| Hypertension | ||||||||||||
| No | Ref. | 1.19 (0.95, 1.50) |
1.17 (0.94, 1.47) |
0.23 | Ref. | 1.06 (0.86, 1.30) |
1.20 (0.96, 1.52) |
0.29 | Ref. | 1.25 (0.94, 1.67) |
1.38 (1.00, 1.91) |
0.06 |
| Yes | Ref. | 0.89 (0.60, 1.30) |
1.17 (0.75, 1.81) |
0.78 | Ref. | 1.45 (0.93, 2.27) |
1.49 (0.98, 2.24) |
0.08 | Ref. | 1.85 (1.01, 3.42) |
1.69 (1.03, 2.78) |
0.04 |
| Diabetes mellitus | ||||||||||||
| No | Ref. | 1.15 (0.93, 1.42) |
1.28 (1.04, 1.57) |
0.04 | Ref. | 1.20 (0.97, 1.49) |
1.27 (0.98, 1.65) |
0.15 | Ref. | 1.27 (0.95, 1.68) |
1.31 (0.94, 1.81) |
0.13 |
| Yes | Ref. | 1.08 (0.68, 1.70) |
0.92 (0.60, 1.42) |
0.55 | Ref. | 1.22 (0.69, 2.15) |
1.28 (0.93, 1.75) |
0.28 | Ref. | 1.38 (0.90, 2.10) |
1.45 (0.94, 2.24) |
0.07 |
Data are presented as ORs (95%CIs).
Adjusted for age, sex, race, educational level, marital status, family poverty income ratio, smoking status, drinking status, physical activity level, BMI, diabetes mellitus, hypertension, and eGFR.
Tertile 1, the lowest; Tertile 2, the median; Tertile 3, the highest; OR, odds ratio; 95% CI, 95% confidence interval; Ref, reference group; BMI, body mass index; eGFR, estimated glomerular filtration rate.