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. 2022 Aug 4;13(5):2537–2550. doi: 10.1002/jcsm.13050

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© 2022 The Authors. Journal of Cachexia, Sarcopenia and Muscle published by John Wiley & Sons Ltd on behalf of Society on Sarcopenia, Cachexia and Wasting Disorders.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Protein and gene expression levels of mitochondrial‐related genes in MS. PGC‐1α protein content and mRNA expression of mitochondrial transcription factors and genes by qPCR were determined in vastus lateralis biopsies of MS patients and healthy controls. (A) Representative Western immunoblot with PGC‐1α protein bands at different molecular weights. Total (B) and individual bands (C) of PGC‐1α protein levels in MS and controls. (D) Quantitative mRNA expression analyses of mitochondria‐related transcription factors and genes (E). *P < 0.05, **P < 0.01. Mean ± SD.