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. 2022 Sep 20;12:947439. doi: 10.3389/fonc.2022.947439

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Copyright © 2022 Jennrich, Pelzer, Tertel, Koska, Vüllings, Thakur, Jendrossek, Timmermann, Giebel and Rudner

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Expression of the tetraspanins CD9 and CD81 in glioma tumor samples correlates with survival of patients with glioma and glioblastoma. Expression (A) and survival analysis (B) of patients with glioblastoma multiforme (GBM) and low-grade glioma (LGG) were performed using data accessible at the GEPIA platform (http://gepia.cancer-pku.cn/). (A) Box plot analysis of CD9 and CD81 expression in GBM (n = 163) and LGG tissue (n = 518) in comparison to in non-malignant brain tissue (normal tissue N, n = 207)). * indicates significance (p < 0.05). (B) High expression of CD9 correlated with shorter survival in patients with LGG, while high expression of CD81 correlated with shorter survival in patients with GBM.