FIGURE 3.

The Effect of HEO on depressive-like behavior treated by CUMS. The experimental schematic diagram (A); Sucrose preference test (B); Forced swimming test (C); Tail suspension test (D); Open field test (E); The elevated plus-maze (Note:The rose red one represent open-arms and the green one represent close-arms) (F). Data were expressed as mean ± SEM (n = 8). ^## p < 0.01 vs control group; *p < 0.05,**p < 0.01 vs the CUMS group. HEO, the essential oil from the fruits of Z. bungeanum Maxim.; SERT, Sertraline; CUMS, chronic unpredictable mild stress.