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. 2022 Sep 20;9:984711. doi: 10.3389/fcvm.2022.984711

Table 2.

Cox models for cardiovascular mortality for logRC, RC, HDL-C, LDL-C (continuous variables) in the pooled cohort.

Model 1
HR (95% CI)
P-value Model 2
HR (95% CI)
P-value Model 3
HR (95% CI)
P-value
LogRC 3.19 (2.17, 4.70) <0.001 2.74 (1.62, 4.61) <0.001 2.82 (1.17, 6.81) 0.021
RC <0.001 <0.001 <0.001
mg/dL 1.01 (1.00, 1.01) 1.01 (1.00, 1.01) 1.01 (1.00, 1.01)
mmol/L 1.30 (1.16, 1.47) 1.36 (1.16, 1.59) 1.39 (1.11, 1.72)
HDL-C 0.064 0.007 0.537
mg/dL 0.99 (0.99, 1.00) 0.99 (0.98, 1.00) 1.00 (0.98, 1.01)
mmol/L 0.78 (0.60, 1.01) 0.64 (0.48, 0.88) 0.85 (0.50, 1.44)
LDL-C 0.707 0.876 0.285
mg/dL 1.00 (1.00, 1.00) 1.00 (1.00, 1.00) 1.00 (1.00, 1.01)
mmol/L 1.02 (0.92, 1.14) 0.99 (0.88, 1.12) 1.12 (0.91, 1.38)

HR, hazard ratio; CI, confidence interval. Model 1: non-adjusted. Model 2: adjusted for age + sex + race + antihypertensive medications + lipid-lowering medications use. Model 3: Model 2 + systolic blood pressure + coronary heart disease + stroke + smoking.