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. 2022 Aug 16;113(10):3330–3346. doi: 10.1111/cas.15480

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© 2022 The Authors. Cancer Science published by John Wiley & Sons Australia, Ltd on behalf of Japanese Cancer Association.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Identification of key RNA splicing regulation related differentially expressed genes (DEGs) for prognosis of colon cancer. (A) 195 RNA splicing regulator related DEGs were selected for subsequent analysis based on the intersection of The Cancer Genome Atlas (TCGA) cohort and GSE41258 dataset. (B) Volcano plot for the 195 DEGs from the TCGA data portal. HR, hazard ratio. (C) Heatmap shows the expression profiles of the four selected RNA splicing regulator related genes in normal and colon cancer samples in the TCGA database