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Estrogen receptor α (ERα)‐positive rate of mammary carcinomas in Brca1 L63X/+ and Brca1 +/+ rats. (A, B) H&E stained tissue sections. (C, D) Immunostained sections for ERα. Brown staining indicates immunoreactivity. Carcinomas that developed in untreated Brca1 L63X/+ (A,C) and Brca1 +/+ (B,D) rats. Scale bar in (A) applies to (A–D). (E,F) ERα‐positive rate of individual mammary carcinomas. Dots, individual data points; black horizontal line, mean; error bars, SD. *p < 0.05, t‐test
