Table 4. Severity and Outcome of Strokes Occurring During Follow-up.
| Cohort | Type of stroke during follow-up | P valuea | |||||||
|---|---|---|---|---|---|---|---|---|---|
| IS | ICH | Unspecified stroke | ICH vs IS in ICH cohort | Recurrent ICH in ICH cohort vs first-ever ICH in comparison cohort | IS in ICH cohort vs IS in comparison cohort | ||||
| No. | % (95% CI) | No. | % (95% CI) | No. | % (95% CI) | ||||
| ICH cohort | |||||||||
| Case fatality rateb | |||||||||
| Day 1 | NRc | NRc | 36 | 6.7 (4.7-9.1) | 0 | 0.0 (0.0-7.0) | <.001 | .001 | .99 |
| Day 7 | 16 | 2.8 (1.6-4.5) | 96 | 17.8 (14.7-21.3) | NRc | NRc | <.001 | .01 | .60 |
| Day 30 | 41 | 7.2 (5.2-9.6) | 154 | 28.6 (24.8-32.6) | 5 | 9.8 (3.3-21.4) | <.001 | .14 | .48 |
| SSS score, groupedd | |||||||||
| Mild (score, 45-58) | 272 | 47.6 (43.5-51.8) | 156 | 29.0 (25.2-33.0) | 21 | 41.2 (27.6-55.8) | <.001 | .002 | <.001 |
| Moderate (score, 30-44) | 147 | 25.7 (22.2-29.5) | 101 | 18.8 (15.6-22.3) | 10 | 19.6 (9.8-33.1) | |||
| Severe (score, 15-29) | 65 | 11.4 (8.9-14.3) | 91 | 16.9 (13.8-20.4) | NRc | NRc | |||
| Very severe (score, ≤14) | 47 | 8.2 (6.1-10.8) | 136 | 25.3 (21.7-29.2) | NRc | NRc | |||
| Missing | 40 | 7.0 (5.1-9.4) | 54 | 10.0 (7.6-12.9) | 13 | 25.5 (14.3-39.6) | |||
| Comparison cohort | |||||||||
| Case fatality rateb | |||||||||
| Day 1 | 65 | 0.5 (0.4-0.7) | 165 | 12.0 (10.3-13.8) | 8 | 1.1 (0.5-2.1) | <.001 | NA | NA |
| Day 7 | 396 | 3.2 (2.9-3.5) | 320 | 23.2 (21.0-25.6) | 33 | 4.4 (3.0-6.1) | <.001 | NA | NA |
| Day 30 | 993 | 8.0 (7.5-8.5) | 441 | 32.0 (29.6-34.6) | 61 | 8.1 (6.2-10.3) | <.001 | NA | NA |
| SSS score, groupedd | |||||||||
| Mild (score, 45-58) | 7370 | 59.4 (58.5-60.2) | 416 | 30.2 (27.8-32.7) | 454 | 60.1 (56.5-63.6) | <.001 | NA | NA |
| Moderate (score, 30-44) | 2487 | 20.0 (19.3-20.7) | 283 | 20.6 (18.4-22.8) | 116 | 15.4 (12.9-18.1) | NA | NA | |
| Severe (score, 15-29) | 1090 | 8.8 (8.3-9.3) | 237 | 17.2 (15.3-19.3) | 56 | 7.4 (5.7-9.5) | NA | NA | |
| Very severe (score, ≤14) | 896 | 7.2 (6.8-7.7) | 373 | 27.1 (24.8-29.5) | 42 | 5.6 (4.0-7.4) | NA | NA | |
| Missing | 573 | 4.6 (4.3-5.0) | 68 | 4.9 (3.9-6.2) | 87 | 11.5 (9.3-14.0) | NA | NA | |
Abbreviations: ICH, intracerebral hemorrhage; IS, ischemic stroke; NA, not applicable; NR, not reported; SSS, Scandinavian Stroke Scale.
a
χ2 test.
b
Percentage of patients who died within 1, 7, and 30 days of admission for stroke. Includes all deaths (ie, in-hospital and out of hospital). Vital status retrieved from Danish Civil Registration System.
c
Not reported to preserve anonymity in view of small cell count.
d
Scandinavian Stroke Scale score at time of hospital admission.