Table 5.
Efficacy in patients with different ECOG PS.
| Overall (n=58) | ECOG PS 0-1 (n=38) | ECOG PS 2 (n=20) | |
|---|---|---|---|
| PR, n(%) | 34 (58.6) | 28 (73.7) | 6 (30.0) |
| SD, n(%) | 18 (31.0) | 9 (23.7) | 9 (45.0) |
| PD, n(%) | 6 (10.4) | 1 (2.6) | 5 (25.0) |
| ORR, % | 58.6 | 73.7 | 30.0 |
| DCR, % | 89.6 | 97.4 | 75.0 |
| mPFS (months) | 6.0 | 8.5 | 3.1 |
| mOS (months) | 10.5 | 15.0 | 4.0 |
| 6-month PFS, % | 47.9 | 75.9 | 5.3 |
| 6-month OS, % | 72.5 | 100.0 | 22.2 |
| 1-year OS, % | 28.9 | 62.5 | 5.9 |
ECOG PS, Eastern Cooperative Oncology Group Performance Status; PR, partial response; SD, stable disease; PD, progressive disease; ORR, objective response rate; DCR, disease control rate; PFS, progression-free survival; OS, overall survival.