TABLE 2.

Comparison of inflammatory biomarkers between groups at the baseline and end of the study¹.

Variables2	Groups		P-value3
	Intervention (n = 33)	Control (n = 32)		P- adjusted4
IL-17 (pg/dl)
Before	25.43 ± 11.36	23.71 ± 9.65	0.24
After	25.46 ± 14.49	25.04 ± 13.89	0.75
Change	0.02 ± 1.19	1.32 ± 1.97	0.19	0.105
P-value5	0.32	0.18
IL-35 (pg/dl)
Before	10.29 ± 4.76	10.81 ± 6.12	0.16
After	10.42 ± 5.16	11.16 ± 5.88	0.62
Change	0.13 ± 0.65	0.35 ± 0.49	0.08	0.124
P-value5	0.376	0.182
CRP (mg/dl)
Before	3.62 ± 2.12	3.24 ± 1.28	0.43
After	2.69 ± 1.78	3.29 ± 2.24	0.38
Change	−0.93 ± 1.62	0.05 ± 1.74	0.03	0.034
P-value5	0.04	0.71
TNF-a (pg/dl)
Before	5.25 ± 3.28	4.68 ± 3.13	0.364
After	3.16 ± 2.78	5.16 ± 3.62	0.089
Change	−2.09 ± 1.88	0.48 ± 2.53	0.015	0.026
P-value5	0.021	0.367
IFN-γ (pg/dl)
BeforeAfterChange	33.17 ± 8.40 19.98 ± 2.57 −13.18 ± 7.33	30.76 ± 7.46 28.83 ± 7.14 −1.93 ± 5.99	0.17 < 0.001 < 0.001	< 0.001
P-value5	< 0.001	0.12

1. CRP, C-reactive protein; IFN-γ, Interferon gamma, IL-17, Interleukin 17; IL-35, Interleukin 35; TNF-α, Tumor necrosis factor-α.

2. Data are presented as mean (SD) or geometric mean (SD).

3. Calculated using one-way ANOVA.

4. Calculated using ANCOVA, adjusted for the effect of age, sex, disease duration and calorie intake.

5. Calculated using paired sample t-test.