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. 2022 Sep 20;12:973282. doi: 10.3389/fcimb.2022.973282

Table 2.

List of the identified DEPs between SC19 vs EGCG treated SC19.

Protein name Functions Ratio (EGCG/SC19) Uniquepeptides Sequence coverage (%)
DNA replication associated
Smc Chromosome partition protein 3.154588 1 38.91
PolC DNA polymerase III 1.830461 2 27.68
DnaK Chaperone protein 0.497069 1 79.9
DnaG DNA primase 1.991800 1 26.51
RpoB DNA-directed RNA polymerase subunit beta 1.897211 1 57.56
DnaB Replication initiation/membrane attachment protein 0.81552 11 30.55
A6M16_07230 Helicase 0.765107 6 50.39
Smc Chromosome partition protein 1.717061 1 39.42
Fic Cell filamentation protein 2.418688 1 23.51
FtsA Cell division protein FtsA 2.256282 1 60.66
Cell wall associated
MurE UDP-N-acetylmuramoyl-L-alanyl-D-glutamate–L-lysine ligase 2.154161 1 30.56
MurAB UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2.035757 1 51.79
Pbp2A Penicillin-binding protein 2A 1.21914 24 40.98
MurB Site-specific tyrosine UDP-N-acetylenolpyruvoylglucosamine reductase 0.743356 9 33.44
Segregation and condensation protein B 0.740106 6 36.48
PbpD Membrane carboxypeptidase (Penicillin-binding protein) 0.709299 2 37.92
Cell wall biosynthesis glycosyltransferase 0.394956 1 19.53
ERS132461_00734 LPXTG cell wall surface protein 1.582084 1 2.72
ERS132461_02224 Cell wall surface anchor family protein 1.240508 1 1.11
Cell membrane associated
ERS132414_00279    Membrane protein 2.123565 1 3.33
ID09_11505    Membrane protein 1.737502 1 6.17
ERS132394_00175    Membrane protein 1.470201 2 16.95
ERS132531_00304    Membrane protein 1.379608 2 6.48
ID09_01605    Membrane protein 0.734679 2 9.94
ID09_07730    Membrane protein 0.729151 6 43.52
ID09_02880    Membrane protein 0.686472 1 2.5
ID09_03715    Membrane protein 0.604128 2 10.49
LI88_12640    Membrane protein 0.585303 2 7.22
A6M16_05425 Multidrug ABC transporter ATP-binding protein 0.656875 1 29.03
yheH_2 Multidrug ABC transporter ATPase and permease 0.654701 1 30.73
yheI_2 Multidrug ABC transporter ATPase/permease 0.802254 18 37.22
tetM Tetracycline resistance 0.746043 12 18.78
PyrP Xanthine/uracil permease 0.530648 1 4.3
GuaB Inosine-5’-monophosphate dehydrogenase 0.742405 1 80.12
Virulence associated
NeuC UDP-N-acetylglucosamine 2-epimerase 0.825171 17 55.17
Sly Thiol-activated cytolysin 0.616023 8 15.58
Cps2B Chain length determinant protein 0.831134 4 52.84
Cps2E Galactosyl transferase 0.769827 12 23.75
Cps2G Glycosyltransferase 0.792496 16 50.65
Cps2J Glycosyltransferase 0.760726 12 34.88
Cps2K Glycosyltransferases involved in cell wall biogenesis 1.240508 13 47.83
Cps2R Acetyltransferase 0.72227 5 28.37
Environmental adaption associated
Ndk Nucleoside diphosphate kinase 0.535681 1 44.53
HPr    Phosphocarrier protein 0.824924 1 59.26
CspA    Cold-shock protein 0.552037 5 58.21
RelA/SpoT    GTP pyrophosphokinase 1.468818 11 47.53