FIGURE 2.

The TBI model plays a leading role in research on the neuroprotective effect of DEX. Therefore, trials with TBI as the model were screened and summarized to explore the neuroprotective mechanism of DEX under the same injury conditions. In the TBI model, the action of DEX involves two main processes, the inflammatory response and oxidative stress, which act on multiple levels of cells, signaling pathways and molecules; oxidative stress process ultimately promotes the release of inflammatory mediators and infiltration of inflammatory cells. Once again, it was confirmed that DEX plays an important role in alleviating inflammation in patients with neurological injury.