Table I.
Demographics of STAN study participants
| BMI category | Lean | Overweight | Obese | p |
|---|---|---|---|---|
| n | 23 (22%) | 31 (31%) | 48 (47%) | |
| % Female | 56.5 | 62.5 | 74.5 | 0.28 |
| Age | 37.35 ± 15.95 | 36.78 ± 12.79 | 38.6 ± 13.48 | 0.84 |
| Race | <0.01 | |||
| Caucasian | 20 (86.9%) | 20 (62.5%) | 23 (48.9%) | |
| African American | 2 (8.7%) | 9 (28.1%) | 22 (46.8%) | |
| Other | 1 (4.4%) | 3 (9.4%) | 2 (4.3%) | |
| Age of asthma onset | 14.09 ± 16.32 | 13.47 ± 12.44 | 15.85 ± 14.17 | 0.74 |
| FEV1 (%predicted) | 89.97 ± 13.16 | 90.82 ± 14.10 | 88.13 ± 15.99 | 0.71 |
| FVC (%predicted) | 97.34 ± 13.24 | 103.10 ±14.58 | 96.88 ± 15.24 | 0.15 |
| FEV1/FVC | 0.92 ± 0.08 | 0.88 ± 0.09 | 0.90 ± 0.08 | 0.08 |
| Closing Index | 0.70 ± 0.26 | 0.68 ± 0.23 | 0.81 ± 0.18 | 0.05 |
| Airway Narrowing | 0.07 ± 0.08 | 0.11 ± 0.06 | 0.07 ± 0.08 | 0.11 |
| PC20 | 3.31 ± 3.78 | 2.23 ± 2.88 | 2.50 ± 3.64 | 0.54 |
| Peak Flow (%predicted) | 87.65 ± 16.22 | 89.13 ± 17.81 | 84.40 ± 18.07 | 0.48 |
| FeNO (ppb) | 39.42 ± 27.7 | 37.69 ± 33.3 | 32.10 ± 29.2 | 0.22 |
| ACT¥ | 15.65 ± 2.72 | 15.84 ± 3.30 | 15.72 ± 3.42 | 0.97 |
| ASUI¥ | 0.69 ± 0.20 | 0.72 ± 0.16 | 0.73 ± 0.19 | 0.70 |
| SNOT22 | 41.5 ± 23.9 | 39.9 ± 21.7 | 43.0 ± 22.7 | 0.83 |
Values are mean ± SD
p-values shown for one-way ANOVA, except for gender and race where a Fischer’s exact test was used.
¥
Higher values indicative of better health
BMI, body mass index; FEV1, forced expiratory volume in 1s; FVC, forced vital capacity; ACT, Asthma Control Test; ASUI. Asthma Symptom Utility Index.