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. 2022 Oct 4;20:437. doi: 10.1186/s12951-022-01637-w

Table 4.

Clinical trials of PDT for urological cancers

Photosensitizers Conditions Locations Status NCT number
TLD1433 NMIBC refractory to BCG Canada Phase 1 (C) NCT03053635
NMIBC refractory to BCG United States; Canada Phase 2 (R) NCT03945162
Photofrin® Superficial BC United States Phase 1/2 (C) NCT00322699
Hexvix® Intermediate or high-risk BC NA Phase 1 (C) NCT01303991
Motexafin Lutetium Adenocarcinoma of the prostate; recurrent PCa; stage I PCa; stage IIA PCa; stage IIB PCa United States Phase 1 (T) NCT00005067
WST09 PCa Canada Phase 2 (C) NCT00305929
Recurrent or persistent localized carcinoma of the prostate following radiation therapy failure Canada Phase 2 (C) NCT00308919
PCa Canada Phase 2/3 (T) NCT00312442
WST11 PCa Canada; France; United Kingdom Phase 2 (C) NCT00707356
PCa United States Phase 1/2 (C) NCT00946881
PCa France; Netherlands; United Kingdom Phase 2 (C) NCT00975429
PCa Belgium; Finland; France; Germany; Italy; Netherlands; Spain; Sweden; Switzerland; United Kingdom Phase 3 (C) NCT01310894
PCa Mexico; Panama; Peru Phase 3 (C) NCT01875393
Localized PCa United States Phase 2 (ANR) NCT03315754
Low Risk PCa France Phase 4 (T) NCT03849365
Localized PCa United States Phase 3 (W) NCT04225299
Upper tract urothelial carcinoma United States Phase 1 (ANR) NCT03617003
Renal cancer United Kingdom Phase 1/2 (T) NCT01573156
Transitional cell cancer of renal pelvis and ureter United States; France Phase 3 (R) NCT04620239
Verteporfin Recurrent PCa United States; Canada; United Kingdom Phase 1 (U) NCT03067051

Data obtained from clinicaltrials.gov (Accessed on April 13, 2022)

NA Not available; C Completed; R: Recruiting; T Terminated; ANR active, not recruiting; W Withdrawn; U Unknown; NMIBC Non-muscle invasive bladder cancer; BC Bladder cancer; PCa Prostate cancer