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. 2022 Oct 4;52(1):201–214. doi: 10.1016/j.gtc.2022.09.003

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Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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Fig. 2 — Histology of liver changes in patients with COVID-19. (A) Steatosis. (B) Mild portal activity. (C) Mild lobular activity. (D) Mild sinusoidal dilatation with increased lymphocytic infiltration. (E) Focal centrilobular hepatic necrosis. (F) Portal arteriolar muscular hyperplasia (left arrow) and hyalinosis of a smaller branch of portal arteriole (right arrow).

([A] Zhao CL, Rapkiewicz A, Maghsoodi-Deerwester M, et al. Pathological findings in the postmortem liver of patients with coronavirus disease 2019 (COVID-19). Human pathology. Mar 2021;109:59-68. https://doi.org/10.1016/j.humpath.2020.11.015 (Ref. 43); [B, C] Chornenkyy Y, Mejia-Bautista M, Brucal M, et al. Liver Pathology and SARS-CoV-2 Detection in Formalin-Fixed Tissue of Patients With COVID-19. American journal of clinical pathology. May 18 2021;155(6):802-814. https://doi.org/10.1093/ajcp/aqab009 (Ref. 55); [D, E] Tian S, Xiong Y, Liu H, et al. Pathological study of the 2019 novel coronavirus disease (COVID-19) through postmortem core biopsies. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. Jun 2020;33(6):1007-1014. https://doi.org/10.1038/s41379-020-0536-x (Ref. 50); [F] Lagana SM, Kudose S, Iuga AC, et al. Hepatic pathology in patients dying of COVID-19: a series of 40 cases including clinical, histologic, and virologic data. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. Nov 2020;33(11):2147-2155. https://doi.org/10.3389/fimmu.2021.676828)