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. 2022 Oct 4;110:103877. doi: 10.1016/j.drugpo.2022.103877

Fig. 2.

Fig 2

A. Methadone- (black) and buprenorphine- (grey) related deaths reported to NPSAD from England which occurred January 2016 – June 2020. B. Linear trend of methadone-related deaths January 2018 – June 2020. The exponential smoothing model for the number of deaths which could have been anticipated in March – June 2020 is indicated (red) along with the lower and upper confidence (95%) bounds. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)