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. 2022 Oct 3;14(10):e29862. doi: 10.7759/cureus.29862

Table 5. Summary of prospective and retrospective clinical studies .

AIRTRIP - Anakinra-Treatment of Recurrent Pericarditis, IRAP - International Registry of Anakinra for Pericarditis

Study Year Patient size Drug Regimen Result
Imazio et al. [18] (IRAP) 2020 224 100 mg/day 91% reduction in Emergency Department visits and 86% reduction in hospitalizations after six months on anakinra compared to prior treatment
Shaukat et al. [21] 2020 34 100 mg/day Anakinra group had a higher rate of resolution of symptoms and in a shorter period of time in comparison to the traditional therapy group.
Brucato et al. [16]  (AIRTRIP) 2016 21 2 mg/kg/day Max:100 mg/day Recurrence of pericarditis was significantly lower in the anakinra group compared to the placebo group.