Table 3.
MC1R haplotypes from 23-locus (SNP1–23)a and depression status in Mexican Americans
| Haplotype | Sequence b | Frequency | Case, Control Ratios | χ2 | P value |
|---|---|---|---|---|---|
| H1 | GGGCGCCGGGCTCGTGGCGGCAG | 0.494 | 174.1:187.9, 187.4:182.6 | 0.477 | 0.4898 |
| H2 | GGGCGCCGGGCTCATGGCGGCAG | 0.318 | 127.3:237.4, 105.3:264.7 | 3.397 | 0.0500 |
| H3 | GTGCGCCGGGCTCGTGGCGGCAG | 0.049 | 16.5: 345.5, 19.2: 350.8 | 0.152 | 0.6965 |
| H4 | GGGCACCGGGCTCGTGGCGGCGG | 0.046 | 14.0: 348.0, 20.0: 350.0 | 0.978 | 0.3227 |
| H5 | GGGCGCCGGGCTCGTGGCGGCGG | 0.024 | 6.3: 355.7, 11.4: 358.6 | 1.365 | 0.2400 |
See Table 1 for definitions of the SNP1–23, and the haplotype is from 5’ to 3’ in MC1R.
The SNPs shown in bold and underlined in the haplotype are different ones compared with most common haplotype H1.