Table 3.
Cluster size thresholds for whole-brain activity and gPPI analyses
| Analysis | Cluster threshold (voxels) |
|---|---|
| Association between TNF-α and activity to angry and fearful faces > shapes | 165 |
| Association between IL-6/CRP and activity to angry and fearful faces > shapes | 160 |
| Association between TNF-α and activity to angry faces > shapes | 164 |
| Association between IL-6/CRP and activity to angry faces > shapes | 151 |
| Association between TNF-α and activity to fearful faces > shapes | 154 |
| Association between IL-6/CRP and activity to fearful faces > shapes | 155 |
| Association between TNF-α and activity to happy faces > shapes | 151 |
| Association between IL-6/CRP and activity to happy faces > shapes | 151 |
| Association between TNF-α and activity to angry and fearful faces > happy faces | 170 |
| Association between IL-6/CRP and activity to angry and fearful faces > happy faces | 160 |
| Association between TNF-α and bilateral amygdala PPI for angry and fearful faces > shapes | 115 |
| Association between IL-6/CRP and bilateral amygdala PPI for angry and fearful faces > shapes | 142 |
| Association between TNF-α and bilateral amygdala PPI for angry faces > shapes | 129 |
| Association between IL-6/CRP and bilateral amygdala PPI for angry faces >shapes | 116 |
| Association between TNF-α and bilateral amygdala PPI for fearful faces > shapes | 137 |
| Association between IL-6/CRP and bilateral amygdala PPI for fearful faces > shapes | 127 |
| Association between TNF-α and bilateral amygdala PPI for angry and fearful faces > happy faces | 135 |
| Association between IL-6/CRP and bilateral amygdala PPI for angry and fearful faces > happy faces | 138 |
| Association between TNF-α and bilateral amygdala PPI for happy faces > shapes | 134 |
| Association between IL-6/CRP and bilateral amygdala PPI for happy faces > shapes | 126 |
| Association between TNF-α x SES and bilateral amygdala PPI for angry and fearful faces > shapes | 118 |
| Association between IL-6/CRP x SES and bilateral amygdala PPI for angry and fearful faces > shapes | 134 |
| Association between TNF-α x gender and bilateral amygdala PPI for angry and fearful faces > shapes | 118 |
| Association between IL-6/CRP x gender and bilateral amygdala PPI for angry and fearful faces > shapes | 140 |
Note: Cluster size threshold was determined using 2-sided thresholding with the first-nearest neighbor clustering (NN1) option. To examine whole-brain effects, we used an uncorrected voxelwise p-value of p<0.002