Table 5.
Results from whole-brain gPPI analyses
| t(77)= | p-uncorrected | Cluster size | Peak coordinates (x, y, z) | Label of region | Direction of association | |
|---|---|---|---|---|---|---|
| Angry and fearful faces > Shapes | ||||||
| TNF-α | 3.96 | <.001 | 144 | (−6, −82, 26) | Left cuneus | Negative |
| 3.95 | <.001 | 147 | (14, −62, 20) | Right cuneus; right calcarine fissure; right precuneus | Negative | |
| 3.88 | <.001 | 119 | (−60, −50, 30) | Left inferior parietal gyrus; left supramarginal gyrus | Negative | |
| IL-6/CRP | 4.37 | <.001 | 154 | (42, −18, 32) | White matter; right postcentral gyrus | Negative |
| 4.18 | <.001 | 191 | (14, −52, 12) | Right precuneus | Negative | |
| Angry > Shapes | ||||||
| IL-6/CRP | 4.01 | <.001 | 172 | (−38, −74, 22) | Left middle occipital gyrus | Negative |
| 3.95 | <.001 | 292 | (12, −50, 12) | Right precuneus; left precuneus | Negative | |
Note: Labels are based on the Automated Anatomical Labeling (AAL) atlas v3. Labels include regions in which 20% or more of the cluster fall within that label.