Table 4.
Volumetric brain regions showing significant differences by diagnostic group.
| ROI | F-test | Direction | T-test |
|---|---|---|---|
| lh_entorhinal_volume | F (2.0, 36.0) = 2.874, p = 0.004 | HV > SCZ | t (25.0) = 3.288, p = 0.009 |
| lh_inferiorparietal_volume | F (2.0, 36.0) = 0.115, p = 0.036 | HV > SCZ | t (27.0) = 3.284, p = 0.009 |
| BD > SCZ | t (25.0) = 4.075, p = 0.001 | ||
| lh_inferiortemporal_volume | F (2.0, 36.0) = 0.609, p = 0.008 | HV > SCZ | t (25.0) = 4.872, p <0.001 |
| lh_lateralorbitofrontal_volume | F (2.0, 36.0) = 0.868, p = 0.008 | HV > SCZ | t (25.0) = 4.545, p <0.001 |
| BD > SCZ | t (27.0) = 3.03, p = 0.016 | ||
| lh_posteriorcingulate_volume | F (2.0, 36.0) = 0.001, p = 0.045 | HV > SCZ | t (25.0) = 3.404, p = 0.007 |
| lh_precuneus_volume | F (2.0, 36.0) =0.007, p = 0.006 | HV > SCZ | t (25.0) = 4.103, p = 0.001 |
| lh_superiorfrontal_volume | F (2.0, 36.0) = 0.013, p = 0.006 | HV > SCZ | t (27.0) = 3.868, p = 0.002 |
| BD > SCZ | t (25.0) = 4.386, p = 0.001 | ||
| lh_supramarginal_volume | F (2.0, 36.0) = 0.028, p = 0.013 | HV > SCZ | t (25.0) = 3.109, p = 0.014 |
| rh_entorhinal_volume | F (2.0, 36.0) = 0.002, p = 0.044 | HV > SCZ | t (25.0) = 4.388, p = 0.001 |
| rh_fusiform_volume | F (2.0, 36.0) = 1.42,p = 0.036 | HV > SCZ | t (25.0) = 3.588, p = 0.004 |
| rh_inferiorparietal_volume | F (2.0, 36.0) = 0.151, p = 0.020 | HV > SCZ | t (27.0) = 3.796, p = 0.002 |
| BD > SCZ | t (25.0) = 4.683, p <0.001 | ||
| rh_inferiortemporal_volume | F (2.0, 36.0) = 0.562, p = 0.004 | HV > SCZ | t (25.0) = 4.917, p <0.001 |
| rh_lateralorbitofrontal_volume | F (2.0, 36.0) = 0.598, p = 0.006 | HV > SCZ | t (25.0) = 4.227, p = 0.001 |
| BD > SCZ | t (27.0) = 3.08,p = 0.014 | ||
| rh_medialorbitofrontal_volume | F (2.0, 36.0) = 0.005, p = 0.025 | HV > SCZ | t (25.0) = 3.236, p = 0.010 |
| rh_precuneus_volume | F (2.0, 36.0) = 0.372, p = 0.005 | HV > SCZ | t (25.0) = 4.177, p = 0.001 |
| rh_superiorfrontal_volume | F (2.0, 36.0) = 0.705, p = 0.006 | HV > SCZ | t (27.0) = 4.24, p = 0.001 |
| BD > SCZ | t (25.0) = 3.372, p = 0.007 | ||
| rh_supramarginal_volume | F (2.0, 36.0) = 0.017, p = 0.017 | HV > SCZ | t (25.0) = 5.021, p <0.001 |
Results from ANOVA (including genotype) and post-hoc t-test are presented. All significant differences were consistent with the BD > HV > SCZ relationship.