Table 1.
Characteristics | Total (N = 97) | SOC plus arbidol (n = 64) | SOC (n = 33) | t or χ2 values | P values |
Age (years) | 46.51 ± 11.23 | 46.16 ± 11.21 | 47.18 ± 11.42 | −0.420∗ | 0.672 |
Male | 44/97 (45.4) | 27/64 (42.2) | 17/33 (51.5) | 0.764† | 0.382 |
Han nationality | 97 (100.0) | 64 (100.0) | 33 (100.0) | ||
Disease severity | –‡ | 0.163 | |||
Mild and moderate | 92/97 (94.8) | 59/64 (92.2) | 33 (100.0) | ||
Severe | 5/97 (5.2) | 5/64 (7.8) | 0 (0) | ||
Coexisting diseases | 34/97 (35.1) | 23/64 (35.9) | 11/33 (33.3) | 0.065† | 0.799 |
Temperature (°C) | 36.69 ± 0.45 | 36.59 ± 0.40 | 36.87 ± 0.48 | −3.040 | 0.003 |
Symptoms | |||||
Fever | 41/97 (42.3) | 21/64 (32.8) | 20/33 (60.6) | 6.583† | 0.009 |
Acute hypoxia | 9/97 (9.3) | 5/64 (7.8) | 4/33 (12.1) | 0.480† | 0.488 |
Oxygen therapy | 13/97 (13.4) | 8/64 (12.5) | 4/33 (12.1) | 0.003† | 0.957 |
Lab examination abnormal | |||||
WBC | 4/51 (7.8) | 2/35 (5.7) | 2/16 (12.5) | –‡ | 0.581 |
LYMPH | 17/51 (33.3) | 13/35 (37.1) | 4/16 (25.0) | –‡ | 0.527 |
PLT | 6/51 (11.8) | 4/35 (11.4) | 2/16 (12.5) | –‡ | 1.000 |
ALT | 7/38 (18.4) | 7/30 (23.3) | 0/8 (0) | –‡ | 0.307 |
AST | 5/38 (13.2) | 4/30 (13.3) | 1/8 (12.5) | –‡ | 1.000 |
ALB | 10/38 (26.3) | 10/30 (33.3) | 0/8 (0) | –‡ | 0.082 |
LDH | 6/36 (16.7) | 5/30 (16.7) | 1/6 (16.7) | –‡ | 1.000 |
CK | 3/36 (8.3) | 2/30 (6.7) | 1/6 (16.7) | –‡ | 0.431 |
CK-MB | 2/36 (5.6) | 2/30 (6.7) | 0/6 (0) | –‡ | 1.000 |
BUN | 4/37 (10.8) | 4/30 (13.3) | 0/7 (0) | –‡ | 0.570 |
CRE | 2/37 (5.4) | 2/30 (6.7) | 0/7 (0) | –‡ | 1.000 |
CRP | 20/52 (38.5) | 17/37 (45.9) | 3/15 (20.0) | –‡ | 0.118 |
CT abnormal | 80/81 (98.8) | 49/50 (98.0) | 31/31 (100.0) | –‡ | 1.000 |
Data are presented as mean ± standard deviation or n (%). ∗t value.†χ2 value. ‡Fisher's exact test. ALB: Albumin; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; BUN: Blood urea nitrogen; CK: Creatine kinase; COVID-19: Coronavirus disease 2019; CRE: Creatinine; CRP: C-reactive protein; CT: Computed tomography; LDH: Lactate dehydrogenase; LYMPH: Lymphocyte count; PLT: Platelet count; SOC: Standard of care; WBC: White blood cell.