Table 4.
Comparisons of EQ-5D-5L index scores, MANSA scores, and ReQoL-10 sum scores by trial group.
| DIALOG+ intervention (N = 236) |
Standard care (N = 232) |
Difference (no adjustment)a |
Difference (with adjustment)b |
|||
|---|---|---|---|---|---|---|
| N c | Mean (SD) | N c | Mean (SD) | Difference | Difference | |
| [min, max] | [min, max] | (95% CI) | (95% CI) | |||
| EQ-5D-5L | ||||||
| Index at baseline | 235 | 0.891 (0.16) | 232 | 0.927 (0.13) | −0.0351* | - |
| [0.173, 1] | [0.008, 1] | (−0.0609, −0.0088) | ||||
| Index at 6 months | 206 | 0.934 (0.13) | 218 | 0.935 (0.12) | −0.0005 | 0.0140 |
| [−0.141, 1] | [0.075, 1] | (−0.0290, 0.0190) | (−0.0083, 0.0355) | |||
| QALYs over 6 monthsd | 206 | 0.458 (0.06) | 218 | 0.465 (0.050) | −0.0074 | 0.0035 |
| [0.095, 0.5] | [0.195, 0.5] | (−0.0190, 0.0027) | (−0.0021, 0.0089) | |||
| MANSA | ||||||
| At baseline | 236 | 4.480 (0.95) | 232 | 4.537 (0.96) | −0.0576 | - |
| [1.917, 7] | [1.083, 6.833] | (−0.2304, 0.1242) | ||||
| At 6 months | 206 | 4.839 (0.98) | 218 | 4.649 (0.97) | 0.1896* | 0.1810* |
| [2, 6.917] | [1, 7] | (0.0061, 0.3645) | (0.0315, 0.3158) | |||
| ReQoL-10 | ||||||
| At baseline | 236 | 25.661 (8.13) | 232 | 25.672 (8.51) | −0.0114 | - |
| [1, 40] | [2, 40] | (−1.6213, 1.3952) | ||||
| At 6 months | 206 | 27.170 (7.88) | 218 | 26.161 (8.31) | 1.0094 | 0.7237 |
| [2, 40] | [3, 40] | (−0.6621, 2.4348) | (−0.2798, 1.9375) | |||
a
Independent t-tests are reported; 95% CI was produced using the bootstrapping method with 1,000 replications; * p < 0.05.
b
Mixed-effects model with baseline outcome measure and covariates (patients’ age, ICD code, and clinicians’ profession) controlled. 95% CI was produced using bootstrapping replication for 1,000 times with bias corrected. * p < 0.05.
c
N refers to the number of participants who responded to each question.
d
Formula used to calculate QALYs over 6 months: QALY = 0.25 X (index at baseline + index at 6 months).