Table 3.
Treatment and outcomes of geriatric patients with traumatic intracranial hemorrhage after a fall
| Variable | DOAC (n = 56) | VKA (n = 431) | No. OAC (n = 1237) | P value | % Missing |
|---|---|---|---|---|---|
| Anticoagulant-specific reversal agents | 28.9% | 60.4% | 0.0% | < 0.005 | 0.0 |
| Vitamin K | 13.5% | 60.4% | 0.0% | < 0.005 | 0.0 |
| Andexanet alfa | 15.4% | 0.0% | 0.0% | < 0.005 | 0.0 |
| Idarucizumab | 5.8% | 0.0% | 0.0% | < 0.005 | 0.0 |
| Neurosurgical intervention | 17.3% | 13.0% | 9.5% | 0.046 | 0.0 |
| Decompressive craniotomy | 9.6% | 7.7% | 5.1% | 0.092 | 0.0 |
| Burr holes | 3.9% | 4.0% | 3.3% | 0.825 | 0.0 |
| Bolt/monitor placement | 0.0% | 1.9% | 2.3% | 0.477 | 0.0 |
| Extraventricular drain placement | 5.8% | 1.3% | 0.8% | 0.003 | 0.0 |
| ICU admission | 39.3% | 47.1% | 26.9% | 0.004 | 0.0 |
| ICU length of stay (Days) | 3 [1–4] | 3 [1–6] | 3 [1–5] | 0.830 | 0.0 |
| Mechanical ventilation assistance | 5.8% | 3.8% | 5.1% | 0.540 | 0.0 |
| Ventilation duration (days) | 2 [1–3] | 2 [1–5] | 2 [1–4] | 0.942 | 0.0 |
| Total hospital length of stay (Days) | 4 [3–8] | 5 [3–9] | 5 [3–8] | 0.148 | 0.0 |
| In-hospital mortality or hospice | 11.5% | 25.0% | 18.2% | 0.006 | 0.0 |
| Mortality at day 3 | 1.9% | 10.9% | 8.8% | 0.088 | 0.0 |
| Discharge to inpatient rehabilitation | 23.9% | 44.3% | 36.8% | 0.010 | 0.0 |
DOAC direct oral anticoagulant, VKA vitamin K antagonist, OAC oral anticoagulant, ICU intensive care unit, IQR interquartile range