Table 4.
Risk estimates for data from 96-hour (minus day 1) wireless pH monitoring off PPI in predicting ability to discontinue PPI
| Metrics | Category | PPI Discontinued | PPI Resumed | OR (95% CI) | p-value |
|---|---|---|---|---|---|
| Total AET 4.0% | Total AET ≤ 4.0% (n 55) | 24 (44%) | 31 (56%) | Reference | |
| Total AET > 4.0% (n 77) | 16 (21%) | 61 (79%) | 0.33 (0.15, 0.71) | 0.006 | |
| Total AET 5.0% | Total AET ≤ 5.0% (n 65) | 26 (40%) | 39 (60%) | Reference | |
| Total AET > 5.0% (n 67) | 14 (21%) | 53 (79%) | 0.40 (0.18, 0.83) | 0.018 | |
| Total AET 6.0% | Total AET ≤ 6.0% (n 81) | 29 (36%) | 52 (64%) | Reference | |
| Total AET > 6.0% (n 51) | 11 (22%) | 40 (78%) | 0.50 (0.21, 1.11) | 0.086 | |
| * Days with AET > 4.0% | 0 days (n 37) | 19 (51%) | 18 (49%) | Reference | |
| 1 day or more (n 95) | 21 (22%) | 74 (78%) | 0.27 (0.12, 0.60) | 0.001 | |
| 2 days or more (69) | 15 (22%) | 54 (78%) | 0.26 (0.11, 0.62) | 0.002 | |
| 3 days (n 41) | 8 (20%) | 33 (81%) | 0.23 (0.08, 0.61) | 0.004 | |
| * Days with AET > 5.0% | 0 days (n 46) | 22 (48%) | 24 (52%) | Reference | |
| 1 day or more (n 86) | 18 (21%) | 68 (79%) | 0.29 (0.13, 0.62) | 0.002 | |
| 2 days or more (n 61) | 14 (23%) | 47 (77%) | 0.32 (0.14, 0.74) | 0.008 | |
| 3 days (n 32) | 5 (16%) | 27 (84%) | 0.20 (0.06, 0.58) | 0.005 | |
| * Days with AET > 6.0% | 0 days (n 55) | 24 (44%) | 31 (56%) | Reference | |
| 1 day or more (n 77) | 16 (21%) | 61 (79%) | 0.34 (0.16, 0.72) | 0.006 | |
| 2 days or more (n 48) | 13 (27%) | 35 (73%) | 0.48 (0.20, 1.09) | 0.083 | |
| 3 days (n 27) | 5 (19%) | 22 (82%) | 0.29 (0.09, 0.84) | 0.030 |
*
Note that risk estimates are for PPI discontinuation with reference to the lowest acid burden group. For these an OR less than 1.0 with a 95% CI not crossing 1.0 indicates a significantly lower odds of PPI discontinuation.