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. 2022 Oct 4;12:431. doi: 10.1038/s41398-022-02198-0

Table 2.

Associations of Maltreatment (CTQ) with biological aging.

AgeAccelPheno AgeAccelGrim
b (95% CI) β p-value b (95% CI) β p-value
All Maltreatment
Model 1 0.12 [0.026, 0.214] 0.272 0.013 0.0006 [−0.017, 0.018] 0.007 0.949
Model 2 0.122 [0.017, 0.226] 0.277 0.023 0.0008 [−0.016, 0.017] 0.011 0.92
Abusive Maltreatment
Model 1 0.208 [0.054, 0.362] 0.288 0.009 0.008 [−0.021, 0.037] 0.061 0.586
Model 2 0.212 [0.038, 0.386] 0.293 0.018 0.003 [−0.024, 0.031] 0.025 0.816
Model 3a 0.192 [−0.014, 0.398] 0.265 0.068 0.005 [−0.028, 0.038] 0.0398 0.752
Neglectful Maltreatment
Model 1 0.157 [−0.027, 0.341] 0.187 0.093 −0.009 [−0.042, 0.025] −0.057 0.61
Model 2 0.153 [−0.042, 0.349] 0.182 0.122 −0.001 [−0.031, 0.029] −0.007 0.943
Model 3b 0.042 [−0.184, 0.269] 0.05 0.709 −0.004 [−0.040, 0.032] −0.027 0.821

Model 1. Unadjusted model.

Model 2. Adjusted for gender, BMI, smoking status, race, household income and DNAm-based markers of immune cell composition.

aModel 3. Model 2 further adjusted for Neglectful Maltreatment score.

bModel 3. Model 2 further adjusted for Abusive Maltreatment score.