Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Oct 4;13:5805. doi: 10.1038/s41467-022-33110-5

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 3 — a UMAP of experimental time distribution and b cluster distribution of mouse PTC at day 2 (t2) and 30 (t30) after IRI. c UMAP showing ribosome gene expression difference and d hypertrophy genes (Top2a, Mcm7, Ccna2, Ccnb2, Tmsb10, S100a11). e UMAP showing E2F-markers (E2f1, E2f7, E2f8) and f YAP1-targets (Ankdr1, Birc5, Ctgf, Cdk1, Ccnb1, Akt1) in PTC. g Matrix plot of PTC at 2 and 30 days after IRI, showing hypertrophy genes. h Monocle2 trajectory of PTC clusters and trajectory of PTC coloured by pseudotime, mean ribosome gene expression difference, cell cycle phases, E2F-markers (E2f1, E2f7, E2f8) and YAP1-targets (Ankdr1, Birc5, Ctgf, Cdk1, Ccnb1, Akt1). i Monocle2 “facet” trajectory showing cluster distribution in order of appearance. j Violin plots showing ribosome distribution in clusters grouped by ribosome gene expression. Median distribution is represented by the white dot; the black bar in the centre of the violin represents the interquartile range between the first and third quartile; the black lines stretched from the bar represent the lower/upper adjacent values defined as first interquartile −1.5 and third interquartile +1.5, respectively. k Bar plot showing the binned normalized counts distribution in each cluster group. IRI ischemia reperfusion injury.