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Summary of the micronucleus test using male ICR mice
| Group | Dose (mg/kg) | PCE/(PCE + NCE) (%) | MNPCE/4000 PCE (%) |
|---|---|---|---|
| Negative control (water) | 0 | 32.3 ± 4.13 | 0.060 ± 0.029 |
| HU033 | 1000 | 31.5 ± 2.29 | 0.035 ± 0.042 |
| 2000 | 29.0 ± 6.42 | 0.045 ± 0.027 | |
| 5000 | 33.2 ± 1.58 | 0.055 ± 0.048 | |
| Positive control (MMC) | 2 | 30.6 ± 3.38 | 5.555* ± 0.571 |
MNPCE micronucleated polychromatic erythrocyte, PCE polychromatic erythrocyte, NCE normochromatic erythrocyte
Significant difference from negative control, * p < 0.01
