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. 2022 Jun 30;12(10):3843–3860. doi: 10.1016/j.apsb.2022.06.013

Figure 7.

Figure 7

SolA exerts neuroprotection in alloxan (ALX)-induced diabetic neuropathy mouse model. (A) Scheme of neuroprotection evaluation of SolA in diabetic neuropathy model. (B) SolA decreased the number of injured neurons by H&E staining (scale bar: 40 μm). Arrows indicate the neuronal synapses. (C) SolA protected neurons from morphological damage by immunohistochemistry staining of MAP-2 (scale bar: 40 μm, n = 6). Arrows indicate the neuronal synapses. (D) SolA had no effect on the serum AGEs level of diabetic mice (n = 3). Data are expressed as the mean ± SEM. ##P < 0.01 vs. control group. N.S. not significant.