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. 2022 Sep 21;12:988458. doi: 10.3389/fonc.2022.988458

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Copyright © 2022 Wei, Deng, Weng, Li, Lan, Li, Ye, Wang, Liu, Ou, Wei, Huang, Xie, Dong and Qu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Variations in the numbers of total circulating tumor cells (CTCs) and each subpopulation before and after concurrent chemoradiotherapy (CCRT). (A) Comparison of the total CTC numbers detected before CCRT, at the end of CCRT, and 3 months after CCRT. (B) Comparison of the numbers of epithelial CTCs detected at the three predesignated time points. (C) Comparison of the numbers of epithelial/mesenchymal (E/M) hybrid CTCs detected at the three predesignated time points. (D) Comparison of the numbers of mesenchymal CTCs detected at the three predesignated time points. The paired-sample Wilcoxon test was performed for between-group comparisons of CTC numbers.