Table 1.
Characteristics of 37,052 men and 15,004 women according to CRF level; the Cooper Center Longitudinal Study, 1978–2016.
| Low CRF (Quintile 1) | Moderate CRF (Quintiles 2–3) | High CRF (Quintiles 4–5) | p for trend | ||
|---|---|---|---|---|---|
| Men | n = 37,052 | n = 4782 | n = 14,858 | n = 17,412 | |
| Age (year) | 45.2 ± 9.2 | 44.0 ± 8.9 | 45.1 ± 9.1 | 45.5 ± 9.4 | <0.001 |
| BMI (kg/m2) | 27.2 ± 4.0 | 31.5 ± 5.6 | 27.8 ± 3.5 | 25.5 ± 2.7 | <0.001 |
| CRF (METs) | 11.6 ± 2.3 | 8.5 ± 1.1 | 10.6 ± 1.1 | 13.4 ± 1.8 | <0.001 |
| Physical activity (MET-min/week) (missing 10,228) | 1150 ± 1354 | 483 ± 1002 | 785 ± 1069 | 1561 ± 1467 | <0.001 |
| Systolic BP (mmHg) | 121.5 ± 12.8 | 124.4 ± 13.5 | 121.8 ± 12.6 | 120.4 ± 12.5 | <0.001 |
| Total cholesterol (mmol/L) | 5.2 ± 1.0 | 5.4 ± 1.1 | 5.3 ± 1.0 | 5.1 ± 1.0 | <0.001 |
| Triglyceride-to-HDL ratio | 3.1 ± 2.2 | 4.4 ± 2.7 | 3.5 ± 2.3 | 2.4 ± 1.7 | <0.001 |
| Glucose (mmol/L) | 5.5 ± 0.9 | 5.8 ± 1.3 | 5.5 ± 1.0 | 5.4 ± 0.6 | <0.001 |
| WBC (109/L) | 6.0 ± 1.4 | 6.8 ± 1.6 | 6.2 ± 1.4 | 5.6 ± 1.2 | <0.001 |
| Current smoking (n (%)) | 6688 (18.1) | 1349 (28.2) | 3230 (21.7) | 2109 (12.1) | <0.001 |
| Total number of deaths | 3409 | 698 | 1495 | 1216 | |
| All-cause mortality rate (per 1000 man-years) | 5.0 | 8.0 | 5.4 | 3.8 | |
| Women | n = 15,004 | n = 1374 | n = 4613 | n = 9017 | |
| Age (year) | 45.2 ± 10.1 | 44.7 ± 10.2 | 45.1 ± 10.2 | 45.4 ± 10.0 | <0.001 |
| BMI (kg/m2) | 24.2 ± 4.6 | 30.1 ± 7.0 | 25.3 ± 4.4 | 22.8 ± 3.0 | <0.001 |
| CRF (METs) | 9.7 ± 2.0 | 6.6 ± 0.9 | 8.4 ± 1.0 | 10.9 ± 1.6 | <0.001 |
| Physical activity (MET-min/week) (missing 3709) | 1196 ± 1382 | 464 ± 908 | 718 ± 1114 | 1509 ± 1445 | <0.001 |
| Systolic BP (mmHg) | 112.7 ± 14.0 | 117.2 ± 15.4 | 113.5 ± 14.2 | 111.6 ± 13.5 | <0.001 |
| Total cholesterol (mmol/L) | 5.1 ± 1.0 | 5.3 ± 1.0 | 5.2 ± 1.0 | 5.0 ± 0.9 | <0.001 |
| Triglyceride-to-HDL ratio | 1.6 ± 1.3 | 2.4 ± 1.7 | 1.9 ± 1.6 | 1.4 ± 0.9 | <0.001 |
| Glucose (mmol/L) | 5.1 ± 0.7 | 5.4 ± 1.2 | 5.2 ± 0.8 | 5.1 ± 0.6 | <0.001 |
| WBC (109/L) | 5.9 ± 1.5 | 6.8 ± 1.6 | 6.2 ± 1.6 | 5.6 ± 1.4 | <0.001 |
| Current smoking (n( %)) | 1291 (8.6) | 213 (15.5) | 548 (11.9) | 530 (5.9) | <0.001 |
| Total number of deaths | 679 | 109 | 265 | 305 | |
| All-cause mortality rate (per 1000 woman-years) | 2.8 | 4.5 | 3.4 | 2.2 |
Note: Variables age through WBC are presented as mean ± SD.
Abbreviations: BMI = body mass index; BP = blood pressure; CRF = cardiorespiratory fitness; HDL = high-density lipoprotein; MET = metabolic equivalent; WBC = white blood cell count.