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. 2022 Sep 21;9:1010693. doi: 10.3389/fcvm.2022.1010693

Table 1.

Pharmacological characteristics of SGLT2 inhibitors available in the market.

SGLT2 inhibitors Therapeutic indication Dosing Age Type of therapy
Canagliflozin Type 2 diabetes mellitus 100 mg once a day Adult patients Monotherapy or association
Dapagliflozin Type 2 diabetes mellitus 10 mg once a day Adult patients; children from Monotherapy or association
Heart failure 10 mg once a day 10 years of age (only for type 2
Chronic kidney disease 10 mg once a day diabetes mellitus)
Empagliflozin Type 2 diabetes mellitus 10 mg once a day Adult patients Monotherapy or association
Heart failure 10 mg once a day
Ertugliflozin Type 2 diabetes mellitus 5 mg or 10 mg once a day Adult patients Monotherapy or association
Sotagliflozin Type 1 diabetes mellitus 200 mg or 400 mg once a day Adult patients Monotherapy or association