Fig. 5.

Heatmaps of Spearman’s correlation analysis between (A) differential genera and fecal metabolites, (B) differential fecal metabolites and serum/fecal parameters, (C) differential genera and serum metabolites, and (D) differential serum metabolites and serum/fecal parameters. Red and green boxes represent positive and negative correlations, respectively. B/F ratio = Bacteroidetes/Firmicutes ratio; FS = Fecal score; TG = triglyceride. The symbol (*) indicates a significant correlation (* p < 0.05, ** p < 0.01, and *** p < 0.001). (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)