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. 2022 Sep 21;10:915846. doi: 10.3389/fped.2022.915846

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Copyright © 2022 van Willigen, van der Hout-van der Jagt, Huberts and van de Vosse.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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A simple schematic overview of the (A) fetal and (B) neonatal circulation with oxygen- and nutrient-rich (red), oxygen- and nutrient-poor (blue), and oxygen- and nutrient-rich and -poor mixed (purple) blood flow direction. AO, aorta; DA, ductus arteriosus; DV, ductus venosus; FO, foramen ovale; HV, hepatic veins; LA, left atrium; LV, left ventricle; PA, pulmonary arteries; PS, portal sinus; PV, pulmonary veins; RA, right atrium; RV, right ventricle; UA, umbilical arteries; UV, umbilical vein; VC, inferior and superior vena cava. The block “organs” represents all other organs, which are not separately mentioned in the figure.