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. 2022 Sep 21;12:988119. doi: 10.3389/fonc.2022.988119

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Copyright © 2022 Charlestin, Fulkerson, Arias Matus, Walker, Carthy and Littlepage

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Aquaporins as a potential predictive biomarker. ROC plotter analysis of AQP6, AQP7, and AQP8 gene expression in treatment responders and non-responders, according to pathological complete response in breast cancer patients with Luminal A subtype tumors and the indicated treatments. (A) AQP6 expression was lower in responders to aromatase inhibitors than in non-responders. (B) AQP7 expression was lower in responders to aromatase inhibitors than in non-responders. (C) AQP8 expression was lower in responders to anthracycline treatment than in non-responders.