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. 2022 Oct 4;24(9):1194–1203. doi: 10.1111/jch.14558

TABLE 1.

The prevalence of primary aldosteronism (PA) (modified from 2016 European Society Practice Guidelines for diagnosis and treatment of PA 22 )

Patient group Prevalence

Moderate/severe hypertension:

The prevalence rates are from Mosso and coworkers 70 and others have reported similar estimates 71 , 72 , 73 , 74 listed in table 2.

The classification of BP for adults (aged > 18 years) was based on the sixth report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. 75

The three stages of hypertension:

A. Stage 1 = SBP 140–159 mm Hg, DBP 90–99 mm Hg

B. Stage 2 = SBP 160–179 mm Hg, DBP 100–109 mm Hg

C. Stage 3 = SBP > 180 mm Hg, DBP ≧110 mm Hg 76

D. If SBP and DBP were in different categories, the higher category was selected for classification.

Overall prevalence: 6.1%

Stage 1 (mild): 2%

Stage 2 (moderate): 8%

Stage 3 (severe): 13%

Resistant hypertension

SBP > 140 mm Hg and DBP > 90 mm Hg despite treatment with three hypertensive medications 29 , 32 , 77 , 78 , 79

The prevalence of PA is often positively correlated with severity of hypertension and the reports showed 17%–23%.
Hypertensive patients with spontaneous or diuretic‐induced hypokalemia. The prevalence of PA in patients with hypertension and serum K < 3.7 mmol/l is 28.1% and rises up to 88.5% in patients with spontaneous hypokalemia of less than 2.5 mmol/l. 37

Hypertension with adrenal incidentaloma 80 , 81 , 82 , 83 , 84 , 85

An adrenal mass detected incidentally during imaging performed for extra‐adrenal reasons.

Median, 2% (range, 1.1%–10%).
Hypertension with obstructive sleep apnea 60 , 67 34% among newly hypertensive patients with obstructive sleep apnea.

Abbreviations: BP, blood pressure; DBP, diastolic blood pressure; SBP, systolic blood pressure.