Table 5.
Logistic regression analysis of CD6 SNP association with CD prognosis (top), UC extent (middle), and ankylosing spondylitis in IBD patients (bottom), corrected for sex and smoking.
| SNP | Model | Genotype | Good prognosis (%) | Poor prognosis (%) | OR (95% CI) | q value |
|---|---|---|---|---|---|---|
| rs12360861 | Log-additive | A alleles (0, 1, 2) | 127 (18.9) | 544 (81.1) | 0.62 (0.45, 0.86) | 0.027 |
| SNP | Model | Genotype | Proctitis (%) | Left/extensive colitis (%) | OR (95% CI) | q value |
| rs17824933 | Recessive | C/C-C/G G/G |
151 (98.7) 2 (1.3) |
758 (93.0) 57 (7.0) |
5.68 (1.37, 23.48) |
0.010 |
| SNP | Model | Genotype | No ankylosing spondylitis (%) | Ankylosing spondylitis (%) | OR (95% CI) | q value |
| rs17824933 | Dominant | C/C C/G-G/G |
456 (54.1) 387 (45.9) |
51 (71.8) 20 (28.2) |
0.45 (0.27, 0.78) |
0.016 |