Table 6.

TCM regulates neuroendocrine administration through the brain-gut axis.

TCM	Model	Methods	Memory	Neuroprotective effect	Reference
Gas	Mice	D-gal	Improved	LPS↓,proinflammatory cytokine↓	(189) Fasina OB, et al. 2022
Se-Ps	Mice	LPS	Improved	pro-inflammatory mediator↓, anti-inflammatory cytokines↑	(190) Wu S,et al. 2022
QWF	Rats	Aβ1-42	Improved	pro-inflammatory mediator↓, Improved the hippocampal morphology	(191) Xiong W, et al. 2022
XAN	Rats	Aβ1-42	Improved	Regulation of neurotransmitter, amino acids, bile acids, and SCFAs metabolism	(192) Zhou H, et al. 2022
OMO	Rats	D-gal Aβ1-42	Improved	Improve neurotransmitter synthesis and secretion	(193) Chen D,et al. 2017
Rg1	Mice	3xTg-AD	/	Linoleic acid metabolism,arachidonic acid metabolism,tryptophan metabolism,sphingolipid metabolism	(194) Li G, et al .2019
HAL	Mice	hyoscine	Improved	cholinergic function↑,pro-inflammatory mediator↓	(195) Li SP, et al.2018
Ge	Mice	Aβ1-42	/	Lysophosphatidylcholine metabolism, phenylalanine metabolism	(196) Li J, et al. 2018
BSTSF	Rats	Aβ1-42	Improved	Linoleic acid metabolism,beta-linolenic acid metabolism,glycerophospholipid metabolism,tryptophan metabolism, arginine, proline metabolism	(197) Zhang Z, et al. 2020
HLJDD	Rats	Aβ25-35	/	Methionine metabolism, glutamine metabolism,tryptophan metabolism	(198) Gu X, et al. 2020

The '↑' means up-regulation and '↓' means down-regulation.