Table 3.

Results of the mediation analysis (n = 6,302)

Effects	Percentage point difference (95% CI)	Percentage of TE, % (95% CI)
Total effect	5.1 (2.3, 7.9)	100
Direct effect †	4.6 (1.7, 7.5)	90.9 (72.7, 97.2)
Indirect effect ‡	0.5 (0.2, 1.0)	9.1 (2.8, 27.3)

Adjusted for age, sex, Charlson Comorbidity Index, type of hospital (Designated Cancer Care Hospitals or others) and prefecture where hospitals are located.

^† Direct effect: the effect of diabetes on adjuvant chemotherapy implementation in the absence of postoperative complications.

^‡ Indirect effect: the effect of diabetes on adjuvant chemotherapy implementation mediated through postoperative complications.

CI, confidence interval; TE, total effect.