Figure 4.

Response of the target tumor size on MRI in patient ZLT-01-08 (A). The longest dimensions judged by the local investigator were 41.5 mm and 40.2 mm at baseline, 30.5 mm and 31.6 mm at 24 weeks, and 25.6 mm and 33.9 mm at 48 weeks. The reduction rates were 15.4% at 24 weeks and 10% at 48 weeks, as judged by the local investigator, and 31.4% at 24 weeks and 30.5% at 48 weeks, as judged by the central committee radiologist. Metabolic response of the target tumor size on FDG-PET in patient ZLT-01-08 (B). Reduction rates were 59.2% at 24 weeks and 70.4% at 48 weeks. MRI, magnetic resonance imaging; FDG-PET, 18F-fluorodeoxyglucose-positron emission tomography.