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| Patient-reported adverse outcome | No. (%) of patients | |
|---|---|---|
| Opioid-sparing protocol (n = 95) | Standard care (n =98) | |
| ≥1 Reported adverse effects | 18 (18.9) | 31 (31.6) |
| Gastrointestinal upset | 12 (12.6) | 17 (17.3) |
| Drowsiness | 7 (7.4) | 20 (20.4) |
| Dizziness | 2 (2.1) | 6 (6.1) |
| Constipation | 2 (2.1) | 5 (5.1) |
| Pruritus | 0 | 3 (3.1) |
| Headaches | 1 (1.1) | 2 (2.0) |
