Table 17.
Five-Year Total, Annual Average Totala, and Average Annual Age-Adjusted Incidence Ratesb with 95% Confidence Intervals for Children and Adolescents (Ages 0-19 Years), Brain and Other Central Nervous System Tumors by Histopathology and Racec, CBTRUS Statistical Report: US Cancer Statistics – NPCR and SEER, 2015-2019
| Histopathology | White | Black | American Indian/Alaska Native | Asian/Pacific Islander | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 5-Year Total | Annual Average | Rate (95% CI) | 5-Year Total | Annual Average | Rate (95% CI) | 5-Year Total | Annual Average | Rate (95% CI) | 5-Year Total | Annual Average | Rate (95% CI) | |
| Diffuse Astrocytic and Oligodendroglial Tumors | 1,677 | 335 | 0.54 (0.52-0.57) | 247 | 49 | 0.36 (0.32-0.41) | 19 | 4 | 0.25 (0.15-0.39) | 74 | 15 | 0.29 (0.23-0.36) |
| Diffuse astrocytoma | 706 | 141 | 0.23 (0.21-0.25) | 94 | 19 | 0.14 (0.11-0.17) | -- | -- | -- | 25 | 5 | 0.10 (0.06-0.14) |
| Anaplastic astrocytoma | 270 | 54 | 0.09 (0.08-0.10) | 38 | 8 | 0.06 (0.04-0.08) | -- | -- | -- | -- | -- | -- |
| Glioblastoma | 539 | 108 | 0.18 (0.16-0.19) | 93 | 19 | 0.14 (0.11-0.17) | -- | -- | -- | 29 | 6 | 0.11 (0.08-0.16) |
| Oligodendroglioma | 120 | 24 | 0.04 (0.03-0.05) | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Anaplastic oligodendroglioma | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Oligoastrocytic tumors | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Other Astrocytic Tumors | 3,467 | 693 | 1.13 (1.10-1.17) | 558 | 112 | 0.82 (0.75-0.89) | 48 | 10 | 0.63 (0.46-0.83) | 111 | 22 | 0.43 (0.35-0.52) |
| Pilocytic astrocytoma | 3,091 | 618 | 1.01 (0.98-1.05) | 481 | 96 | 0.70 (0.64-0.77) | -- | -- | -- | 94 | 19 | 0.37 (0.30-0.45) |
| Unique astrocytoma variants | 376 | 75 | 0.12 (0.11-0.14) | 77 | 15 | 0.11 (0.09-0.14) | -- | -- | -- | 17 | 3 | 0.07 (0.04-0.11) |
| Malignant | 193 | 39 | 0.06 (0.05-0.07) | 51 | 10 | 0.07 (0.06-0.10) | -- | -- | -- | -- | -- | -- |
| Non-Malignant | 183 | 37 | 0.06 (0.05-0.07) | 26 | 5 | 0.04 (0.03-0.06) | -- | -- | -- | -- | -- | -- |
| Ependymal Tumors | 938 | 188 | 0.31 (0.29-0.33) | 153 | 31 | 0.22 (0.19-0.26) | -- | -- | -- | 41 | 8 | 0.16 (0.11-0.22) |
| Malignant | 187 | 37 | 0.06 (0.05-0.07) | 16 | 3 | 0.02 (0.01-0.04) | -- | -- | -- | -- | -- | -- |
| Non-Malignant | 751 | 150 | 0.24 (0.23-0.26) | 137 | 27 | 0.20 (0.17-0.24) | -- | -- | -- | -- | -- | -- |
| Other Gliomas | 2,439 | 488 | 0.80 (0.77-0.83) | 457 | 91 | 0.67 (0.61-0.74) | 29 | 6 | 0.38 (0.25-0.54) | 105 | 21 | 0.41 (0.33-0.49) |
| Glioma malignant, NOS | 2,418 | 484 | 0.79 (0.76-0.82) | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Other neuroepithelial tumors | 21 | 4 | 0.01 (0.00-0.01) | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Neuronal and Mixed Neuronal-Glial Tumors | 1,640 | 328 | 0.53 (0.51-0.56) | 277 | 55 | 0.41 (0.36-0.46) | 21 | 4 | 0.28 (0.17-0.42) | 82 | 16 | 0.32 (0.25-0.40) |
| Malignant | 1,540 | 308 | 0.50 (0.48-0.53) | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Non-Malignant | 100 | 20 | 0.03 (0.03-0.04) | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Choroid Plexus Tumors | 324 | 65 | 0.11 (0.09-0.12) | 48 | 10 | 0.07 (0.05-0.09) | -- | -- | -- | -- | -- | -- |
| Malignant | 249 | 50 | 0.08 (0.07-0.09) | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Non-Malignant | 75 | 15 | 0.02 (0.02-0.03) | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Tumors of the Pineal Region | 145 | 29 | 0.05 (0.04-0.06) | 51 | 10 | 0.07 (0.06-0.10) | -- | -- | -- | -- | -- | -- |
| Malignant | 29 | 6 | 0.01 (0.01-0.01) | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Non-Malignant | 116 | 23 | 0.04 (0.03-0.05) | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Embryonal Tumors | 1,825 | 365 | 0.60 (0.57-0.63) | 284 | 57 | 0.41 (0.37-0.47) | 26 | 5 | 0.34 (0.22-0.49) | 106 | 21 | 0.41 (0.34-0.50) |
| Medulloblastoma | 1,289 | 258 | 0.42 (0.40-0.45) | 170 | 34 | 0.25 (0.21-0.29) | -- | -- | -- | 75 | 15 | 0.29 (0.23-0.36) |
| Atypical teratoid/rhabdoid tumor | 280 | 56 | 0.09 (0.08-0.10) | 55 | 11 | 0.08 (0.06-0.10) | -- | -- | -- | -- | -- | -- |
| All other embryonal | 256 | 51 | 0.08 (0.07-0.09) | 59 | 12 | 0.09 (0.07-0.11) | -- | -- | -- | -- | -- | -- |
| Tumors of Cranial and Spinal Nerves | 915 | 183 | 0.30 (0.28-0.32) | 130 | 26 | 0.19 (0.16-0.23) | -- | -- | -- | 43 | 9 | 0.17 (0.12-0.22) |
| Nerve sheath tumors | -- | -- | -- | 130 | 26 | 0.19 (0.16-0.23) | -- | -- | -- | 43 | 9 | 0.17 (0.12-0.22) |
| Other tumors of cranial and spinal nerves | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Malignant | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Non-Malignant | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Tumors of Meninges | 974 | 195 | 0.32 (0.30-0.34) | 177 | 35 | 0.26 (0.22-0.30) | -- | -- | -- | 41 | 8 | 0.16 (0.11-0.22) |
| Meningiomas | 520 | 104 | 0.17 (0.15-0.18) | 103 | 21 | 0.15 (0.12-0.18) | -- | -- | -- | 17 | 3 | 0.07 (0.04-0.11) |
| Malignant | 502 | 100 | 0.16 (0.15-0.18) | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Non-Malignant | 18 | 4 | 0.01 (0.00-0.01) | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Mesenchymal tumors | -- | -- | -- | 74 | 15 | 0.11 (0.09-0.14) | -- | -- | -- | -- | -- | -- |
| Primary melanocytic lesions | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Malignant | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Non-Malignant | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Lymphomas and Hematopoietic Neoplasms | 95 | 19 | 0.03 (0.03-0.04) | 16 | 3 | 0.02 (0.01-0.04) | -- | -- | -- | -- | -- | -- |
| Lymphoma | 95 | 19 | 0.03 (0.03-0.04) | 16 | 3 | 0.02 (0.01-0.04) | -- | -- | -- | -- | -- | -- |
| Other hematopoietic neoplasms | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Germ Cell Tumors | 640 | 128 | 0.21 (0.19-0.22) | 101 | 20 | 0.15 (0.12-0.18) | -- | -- | -- | 81 | 16 | 0.31 (0.25-0.39) |
| Malignant | 68 | 14 | 0.02 (0.02-0.03) | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Non-Malignant | 572 | 114 | 0.19 (0.17-0.20) | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Tumors of Sellar Region | 3,407 | 681 | 1.10 (1.06-1.13) | 657 | 131 | 0.96 (0.89-1.04) | 55 | 11 | 0.73 (0.55-0.95) | 149 | 30 | 0.58 (0.49-0.68) |
| Tumors of the pituitary | 2,820 | 564 | 0.90 (0.87-0.94) | 518 | 104 | 0.76 (0.70-0.83) | -- | -- | -- | 114 | 23 | 0.44 (0.36-0.53) |
| Malignant | 2,820 | 564 | 0.90 (0.87-0.94) | 518 | 104 | 0.76 (0.70-0.83) | -- | -- | -- | 114 | 23 | 0.44 (0.36-0.53) |
| Non-Malignant | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Craniopharyngioma | 587 | 117 | 0.19 (0.18-0.21) | 139 | 28 | 0.20 (0.17-0.24) | -- | -- | -- | 35 | 7 | 0.14 (0.09-0.19) |
| Unclassified Tumors | 1,170 | 234 | 0.38 (0.36-0.40) | 176 | 35 | 0.26 (0.22-0.30) | -- | -- | -- | 31 | 6 | 0.12 (0.08-0.17) |
| Hemangioma | 404 | 81 | 0.13 (0.12-0.14) | 42 | 8 | 0.06 (0.04-0.08) | -- | -- | -- | -- | -- | -- |
| Neoplasm, unspecified | 624 | 125 | 0.20 (0.19-0.22) | 104 | 21 | 0.15 (0.12-0.19) | -- | -- | -- | 16 | 3 | 0.06 (0.04-0.10) |
| Malignant | 469 | 94 | 0.15 (0.14-0.17) | 70 | 14 | 0.10 (0.08-0.13) | -- | -- | -- | -- | -- | -- |
| Non-Malignant | 155 | 31 | 0.05 (0.04-0.06) | 34 | 7 | 0.05 (0.03-0.07) | -- | -- | -- | -- | -- | -- |
| All other | 142 | 28 | 0.05 (0.04-0.05) | 30 | 6 | 0.04 (0.03-0.06) | -- | -- | -- | -- | -- | -- |
| Malignant | 116 | 23 | 0.04 (0.03-0.05) | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Non-Malignant | 26 | 5 | 0.01 (0.01-0.01) | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| TOTAL d | 19,656 | 3,931 | 6.39 (6.30-6.48) | 3,332 | 666 | 4.89 (4.72-5.06) | 257 | 51 | 3.38 (2.98-3.82) | 894 | 179 | 3.47 (3.25-3.71) |
| Non-Malignant | 8,552 | 1,710 | 2.77 (2.71-2.82) | 1,473 | 295 | 2.16 (2.05-2.28) | 118 | 24 | 1.56 (1.29-1.87) | 367 | 73 | 1.42 (1.28-1.58) |
| Malignant | 11,104 | 2,221 | 3.63 (3.56-3.70) | 1,859 | 372 | 2.73 (2.60-2.85) | 139 | 28 | 1.82 (1.53-2.15) | 527 | 105 | 2.05 (1.88-2.23) |
aAnnual average cases are calculated by dividing the five-year total by five.
bRates are per 100,000 and are age-adjusted to the 2000 US standard population.
cIndividuals with unknown race were excluded (N = 1200).
dRefers to all brain tumors including histopathologies not presented in this table.
-- Counts and rates are not presented when fewer than 16 cases were reported for the specific category. The suppressed cases are included in the counts and rates for totals.
Abbreviations: CBTRUS, Central Brain Tumor Registry of the United States; NPCR, National Program of Cancer Registries; SEER, Surveillance, Epidemiology, and End Results Program; CI, confidence interval; NOS, not otherwise specified.