Table 18.
Five-Year Total, Annual Average Totala, and Average Annual Age-Adjusted Incidence Ratesb with 95% Confidence Intervals for All Brain and Other Central Nervous System Tumors by Histopathology, Hispanic Ethnicityc, and Race, CBTRUS Statistical Report: US Cancer Statistics – NPCR and SEER, 2015-2019
| Histopathology | Non-Hispanic | All Hispanic | White Hispanic | Black Hispanic | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 5-Year Total | Annual Average | Rate (95% CI) | 5-Year Total | Annual Average | Rate (95% CI) | 5-Year Total | Annual Average | Rate (95% CI) | 5-Year Total | Annual Average | Rate (95% CI) | |
| Diffuse Astrocytic and Oligodendroglial Tumors | 76,233 | 15,247 | 4.67 (4.64-4.71) | 7,779 | 1,556 | 3.49 (3.40-3.57) | 7,125 | 1,425 | 3.52 (3.43-3.60) | 208 | 42 | 2.00 (1.72-2.32) |
| Diffuse astrocytoma | 6,753 | 1,351 | 0.49 (0.47-0.50) | 881 | 176 | 0.34 (0.31-0.36) | 795 | 159 | 0.34 (0.31-0.36) | 23 | 5 | 0.16 (0.10-0.25) |
| Anaplastic astrocytoma | 6,363 | 1,273 | 0.44 (0.43-0.45) | 683 | 137 | 0.27 (0.25-0.29) | 616 | 123 | 0.27 (0.25-0.29) | 24 | 5 | 0.18 (0.11-0.28) |
| Glioblastoma | 57,829 | 11,566 | 3.36 (3.33-3.39) | 5,429 | 1,086 | 2.59 (2.52-2.66) | 4,999 | 1,000 | 2.61 (2.54-2.69) | 148 | 30 | 1.58 (1.31-1.87) |
| Oligodendroglioma | 3,209 | 642 | 0.24 (0.24-0.25) | 478 | 96 | 0.18 (0.16-0.19) | 431 | 86 | 0.18 (0.16-0.20) | -- | -- | -- |
| Anaplastic oligodendroglioma | 1,617 | 323 | 0.12 (0.11-0.12) | 254 | 51 | 0.10 (0.09-0.11) | 233 | 47 | 0.10 (0.09-0.11) | -- | -- | -- |
| Oligoastrocytic tumors | 462 | 92 | 0.03 (0.03-0.04) | 54 | 11 | 0.02 (0.02-0.03) | 51 | 10 | 0.02 (0.02-0.03) | -- | -- | -- |
| Other Astrocytic Tumors | 5,231 | 1,046 | 0.46 (0.45-0.47) | 1,021 | 204 | 0.30 (0.28-0.32) | 907 | 181 | 0.30 (0.28-0.32) | 26 | 5 | 0.15 (0.09-0.23) |
| Pilocytic astrocytoma | 4,494 | 899 | 0.40 (0.39-0.41) | 845 | 169 | 0.25 (0.23-0.26) | 748 | 150 | 0.25 (0.23-0.26) | 21 | 4 | 0.12 (0.07-0.20) |
| Unique astrocytoma variants | 737 | 147 | 0.06 (0.06-0.07) | 176 | 35 | 0.06 (0.05-0.07) | 159 | 32 | 0.06 (0.05-0.07) | -- | -- | -- |
| Non-Malignant | 301 | 60 | 0.03 (0.02-0.03) | 80 | 16 | 0.02 (0.02-0.03) | 71 | 14 | 0.02 (0.02-0.03) | -- | -- | -- |
| Malignant | 436 | 87 | 0.04 (0.03-0.04) | 96 | 19 | 0.03 (0.03-0.04) | 88 | 18 | 0.03 (0.03-0.04) | -- | -- | -- |
| Ependymal Tumors | 5,893 | 1,179 | 0.43 (0.42-0.44) | 1,018 | 204 | 0.36 (0.34-0.39) | 912 | 182 | 0.36 (0.34-0.39) | 27 | 5 | 0.18 (0.11-0.28) |
| Non-Malignant | 2,615 | 523 | 0.19 (0.18-0.19) | 387 | 77 | 0.15 (0.13-0.16) | 339 | 68 | 0.14 (0.13-0.16) | -- | -- | -- |
| Malignant | 3,278 | 656 | 0.25 (0.24-0.25) | 631 | 126 | 0.22 (0.20-0.24) | 573 | 115 | 0.22 (0.20-0.24) | -- | -- | -- |
| Other Gliomas | 7,598 | 1,520 | 0.57 (0.56-0.59) | 1,256 | 251 | 0.45 (0.43-0.48) | 1,097 | 219 | 0.44 (0.41-0.47) | 57 | 11 | 0.43 (0.31-0.58) |
| Glioma malignant, NOS | 7,519 | 1,504 | 0.57 (0.55-0.58) | 1,234 | 247 | 0.44 (0.42-0.47) | 1,077 | 215 | 0.43 (0.41-0.46) | 57 | 11 | 0.43 (0.31-0.58) |
| Other neuroepithelial tumors | 79 | 16 | 0.01 (0.00-0.01) | 22 | 4 | 0.01 (0.00-0.01) | 20 | 4 | 0.01 (0.00-0.01) | -- | -- | -- |
| Non-Malignant | 34 | 7 | 0.00 (0.00-0.00) | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Malignant | 45 | 9 | 0.00 (0.00-0.00) | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Neuronal and Mixed Neuronal-Glial Tumors | 4,558 | 912 | 0.37 (0.35-0.38) | 781 | 156 | 0.25 (0.23-0.27) | 688 | 138 | 0.25 (0.23-0.27) | 31 | 6 | 0.19 (0.12-0.27) |
| Non-Malignant | 3,729 | 746 | 0.31 (0.30-0.32) | 650 | 130 | 0.20 (0.19-0.22) | 569 | 114 | 0.20 (0.18-0.22) | -- | -- | -- |
| Malignant | 829 | 166 | 0.06 (0.05-0.06) | 131 | 26 | 0.05 (0.04-0.06) | 119 | 24 | 0.05 (0.04-0.06) | -- | -- | -- |
| Choroid Plexus Tumors | 665 | 133 | 0.05 (0.05-0.06) | 162 | 32 | 0.05 (0.04-0.06) | 143 | 29 | 0.05 (0.04-0.06) | -- | -- | -- |
| Non-Malignant | 578 | 116 | 0.05 (0.04-0.05) | 128 | 26 | 0.04 (0.04-0.05) | 114 | 23 | 0.04 (0.03-0.05) | -- | -- | -- |
| Malignant | 87 | 17 | 0.01 (0.01-0.01) | 34 | 7 | 0.01 (0.01-0.01) | 29 | 6 | 0.01 (0.01-0.01) | -- | -- | -- |
| Tumors of the Pineal Region | 659 | 132 | 0.05 (0.05-0.06) | 110 | 22 | 0.04 (0.03-0.05) | 100 | 20 | 0.04 (0.03-0.05) | -- | -- | -- |
| Non-Malignant | 272 | 54 | 0.02 (0.02-0.02) | 35 | 7 | 0.01 (0.01-0.02) | 31 | 6 | 0.01 (0.01-0.02) | -- | -- | -- |
| Malignant | 387 | 77 | 0.03 (0.03-0.03) | 75 | 15 | 0.02 (0.02-0.03) | 69 | 14 | 0.03 (0.02-0.03) | -- | -- | -- |
| Embryonal Tumors | 2,453 | 491 | 0.22 (0.21-0.23) | 717 | 143 | 0.21 (0.19-0.23) | 651 | 130 | 0.21 (0.20-0.23) | 22 | 4 | 0.10 (0.06-0.16) |
| Tumors of Cranial and Spinal Nerves | 33,525 | 6,705 | 2.15 (2.13-2.18) | 3,523 | 705 | 1.45 (1.40-1.51) | 3,120 | 624 | 1.42 (1.37-1.48) | 96 | 19 | 0.83 (0.66-1.03) |
| Nerve sheath tumors | 33,495 | 6,699 | 2.15 (2.13-2.18) | 3,520 | 704 | 1.45 (1.40-1.50) | -- | -- | -- | 96 | 19 | 0.83 (0.66-1.03) |
| Non-Malignant | 33,329 | 6,666 | 2.14 (2.12-2.16) | 3,475 | 695 | 1.43 (1.39-1.49) | -- | -- | -- | -- | -- | -- |
| Malignant | 166 | 33 | 0.01 (0.01-0.01) | 45 | 9 | 0.02 (0.01-0.02) | -- | -- | -- | -- | -- | -- |
| Other tumors of cranial and spinal nerves | 30 | 6 | 0.00 (0.00-0.00) | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Tumors of Meninges | 165,351 | 33,070 | 9.97 (9.92-10.02) | 19,054 | 3,811 | 9.33 (9.20-9.47) | 17,215 | 3,443 | 9.25 (9.10-9.39) | 544 | 109 | 5.98 (5.45-6.54) |
| Meningiomas | 160,230 | 32,046 | 9.62 (9.57-9.66) | 18,217 | 3,643 | 9.02 (8.88-9.15) | 16,462 | 3,292 | 8.93 (8.79-9.07) | 532 | 106 | 5.88 (5.35-6.43) |
| Non-Malignant | 158,843 | 31,769 | 9.53 (9.48-9.58) | 17,989 | 3,598 | 8.90 (8.77-9.04) | 16,250 | 3,250 | 8.81 (8.67-8.96) | -- | -- | -- |
| Malignant | 1,387 | 277 | 0.08 (0.08-0.09) | 228 | 46 | 0.11 (0.10-0.13) | 212 | 42 | 0.11 (0.10-0.13) | -- | -- | -- |
| Mesenchymal tumors | 4,989 | 998 | 0.35 (0.34-0.36) | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Non-Malignant | 4,351 | 870 | 0.30 (0.29-0.31) | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Malignant | 638 | 128 | 0.04 (0.04-0.05) | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Primary melanocytic lesions | 132 | 26 | 0.01 (0.01-0.01) | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Non-Malignant | 50 | 10 | 0.00 (0.00-0.00) | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Malignant | 82 | 16 | 0.01 (0.00-0.01) | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Lymphomas and Hematopoietic Neoplasms | 7,461 | 1,492 | 0.44 (0.43-0.45) | 1,064 | 213 | 0.51 (0.48-0.55) | 997 | 199 | 0.53 (0.49-0.56) | 17 | 3 | 0.18 (0.10-0.29) |
| Lymphoma | 7,427 | 1,485 | 0.44 (0.43-0.45) | 1,055 | 211 | 0.51 (0.48-0.54) | 989 | 198 | 0.52 (0.49-0.56) | 17 | 3 | 0.18 (0.10-0.29) |
| Other hematopoietic neoplasms | 34 | 7 | 0.00 (0.00-0.00) | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Germ Cell Tumors | 997 | 199 | 0.09 (0.08-0.09) | 283 | 57 | 0.08 (0.07-0.09) | 251 | 50 | 0.08 (0.07-0.09) | -- | -- | -- |
| Non-Malignant | 137 | 27 | 0.01 (0.01-0.01) | 33 | 7 | 0.01 (0.01-0.02) | 30 | 6 | 0.01 (0.01-0.02) | -- | -- | -- |
| Malignant | 860 | 172 | 0.08 (0.07-0.08) | 250 | 50 | 0.07 (0.06-0.08) | 221 | 44 | 0.07 (0.06-0.08) | -- | -- | -- |
| Tumors of Sellar Region | 66,389 | 13,278 | 4.58 (4.55-4.62) | 13,607 | 2,721 | 5.33 (5.24-5.43) | 12,037 | 2,407 | 5.23 (5.14-5.33) | 486 | 97 | 3.85 (3.49-4.24) |
| Tumors of the pituitary | 63,773 | 12,755 | 4.39 (4.35-4.43) | 13,090 | 2,618 | 5.15 (5.06-5.24) | 11,579 | 2,316 | 5.05 (4.96-5.15) | 462 | 92 | 3.71 (3.35-4.09) |
| Non-Malignant | 63,682 | 12,736 | 4.38 (4.35-4.42) | 13,073 | 2,615 | 5.14 (5.05-5.23) | -- | -- | -- | 462 | 92 | 3.71 (3.35-4.09) |
| Malignant | 91 | 18 | 0.01 (0.00-0.01) | 17 | 3 | 0.01 (0.00-0.01) | -- | -- | -- | -- | -- | -- |
| Craniopharyngioma | 2,616 | 523 | 0.19 (0.18-0.20) | 517 | 103 | 0.18 (0.17-0.20) | 458 | 92 | 0.18 (0.16-0.20) | 24 | 5 | 0.14 (0.09-0.22) |
| Unclassified Tumors | 15,998 | 3,200 | 1.03 (1.01-1.04) | 2,406 | 481 | 1.08 (1.03-1.13) | 2,159 | 432 | 1.07 (1.03-1.12) | 60 | 12 | 0.56 (0.41-0.74) |
| Hemangioma | 3,525 | 705 | 0.25 (0.24-0.26) | 690 | 138 | 0.26 (0.24-0.28) | 620 | 124 | 0.26 (0.24-0.29) | 22 | 4 | 0.16 (0.10-0.25) |
| Neoplasm, unspecified | 12,045 | 2,409 | 0.75 (0.73-0.76) | 1,602 | 320 | 0.77 (0.73-0.81) | 1,434 | 287 | 0.77 (0.72-0.81) | 37 | 7 | 0.39 (0.27-0.56) |
| Non-Malignant | 5,999 | 1,200 | 0.39 (0.38-0.40) | 955 | 191 | 0.42 (0.39-0.45) | 834 | 167 | 0.40 (0.38-0.43) | 26 | 5 | 0.29 (0.18-0.44) |
| Malignant | 6,046 | 1,209 | 0.36 (0.35-0.37) | 647 | 129 | 0.36 (0.33-0.39) | 600 | 120 | 0.36 (0.33-0.39) | -- | -- | -- |
| All other | 428 | 86 | 0.03 (0.03-0.04) | 114 | 23 | 0.04 (0.04-0.05) | 105 | 21 | 0.04 (0.04-0.05) | -- | -- | -- |
| Non-Malignant | 379 | 76 | 0.03 (0.02-0.03) | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| Malignant | 49 | 10 | 0.00 (0.00-0.01) | -- | -- | -- | -- | -- | -- | -- | -- | -- |
| TOTAL d | 393,011 | 78,602 | 25.09 (25.01-25.17) | 52,781 | 10,556 | 22.95 (22.74-23.16) | 47,402 | 9,480 | 22.76 (22.55-22.98) | 1,591 | 318 | 14.55 (13.77-15.35) |
| Malignant | 112,404 | 22,481 | 7.25 (7.21-7.30) | 13,941 | 2,788 | 5.85 (5.75-5.96) | 12,699 | 2,540 | 5.91 (5.80-6.02) | 380 | 76 | 3.23 (2.87-3.61) |
| Non-Malignant d | 280,607 | 56,121 | 17.84 (17.77-17.90) | 38,840 | 7,768 | 17.09 (16.92-17.27) | 34,703 | 6,941 | 16.86 (16.67-17.04) | 1,211 | 242 | 11.32 (10.63-12.03) |
aAnnual average cases are calculated by dividing the five-year total by five.
bRates are per 100,000 and are age-adjusted to the 2000 US standard population.
cHispanic ethnicity is not mutually exclusive of race; Classified using the North American Association of Central Cancer Registries Hispanic Identification Algorithm, version 2 (NHIA v2).
dRefers to all brain tumors including histopathologies not presented in this table.
-- Counts and rates are not presented when fewer than 16 cases were reported for the specific category. The suppressed cases are included in the counts and rates for totals.
Abbreviations: CBTRUS, Central Brain Tumor Registry of the United States; NPCR, National Program of Cancer Registries; SEER, Surveillance, Epidemiology, and End Results Program; CI, confidence interval; NOS, not otherwise specified.