Table 21.
Estimated Number of Casesa,b in the United States of Brain and Other Central Nervous System Tumors Overall and by Behavior and Histopathologyc for Diagnosis Years 2022 and 2023
| Histopathology | 2022 | 2023 | ||||
|---|---|---|---|---|---|---|
| Malignant | Non-Malignant | Total | Malignant | Non-Malignant | Total | |
| Diffuse Astrocytic and Oligodendroglial Tumors | -- | -- | 17,760 | -- | -- | 17,950 |
| Diffuse astrocytoma | -- | -- | 1,440 | -- | -- | 1,420 |
| Anaplastic astrocytoma | -- | -- | 1,090 | -- | -- | 1,020 |
| Glioblastoma | -- | -- | 14,190 | -- | -- | 14,490 |
| Oligodendroglioma | -- | -- | 660 | -- | -- | 650 |
| Anaplastic oligodendroglioma | -- | -- | 390 | -- | -- | 390 |
| Oligoastrocytic tumors | -- | -- | -- | -- | -- | -- |
| Other Astrocytic Tumors | 1,260 | 310 | 1,560 | 1,270 | 350 | 1,620 |
| Pilocytic astrocytoma | 1,130 | 220 | 1,340 | 1,130 | 260 | 1,400 |
| Unique astrocytoma variants | 130 | 90 | 220 | 130 | 90 | 230 |
| Ependymal Tumors | 710 | 680 | 1,390 | 700 | 690 | 1,390 |
| Other Gliomas | -- | -- | 1,990 | -- | -- | 2,030 |
| Glioma malignant, NOS | -- | 1,970 | -- | 2,010 | ||
| Other neuroepithelial tumors | -- | -- | -- | -- | -- | -- |
| Neuronal and Mixed Neuronal-Glial Tumors | 220 | 980 | 1,200 | 220 | 1,000 | 1,220 |
| Choroid Plexus Tumors | -- | -- | 170 | -- | -- | 170 |
| Tumors of the Pineal Region | 110 | 70 | 180 | 110 | 70 | 180 |
| Embryonal Tumors | -- | -- | 560 | -- | -- | 550 |
| Tumors of Cranial and Paraspinal Nerves | -- | -- | 6,380 | -- | -- | 6,190 |
| Nerve sheath tumors | -- | -- | 6,380 | -- | -- | 6,190 |
| Other tumors of cranial and paraspinal nerves | -- | -- | -- | -- | ||
| Tumors of Meninges | 470 | 41,600 | 42,060 | 460 | 42,710 | 43,170 |
| Meningiomas | 280 | 40,820 | 41,110 | 270 | 41,980 | 42,260 |
| Mesenchymal tumors | 160 | 760 | 920 | 160 | 710 | 870 |
| Primary melanocytic lesions | -- | -- | -- | -- | -- | -- |
| Lymphomas and Hematopoietic Neoplasms | -- | -- | 1,870 | -- | -- | 1,900 |
| Lymphoma | -- | -- | 1,860 | -- | -- | 1,890 |
| Other hematopoietic neoplasms | -- | -- | -- | -- | -- | -- |
| Germ Cell Tumors | -- | -- | 260 | -- | -- | 270 |
| Tumors of Sellar Region | -- | -- | 14,830 | -- | -- | 14,560 |
| Tumors of the pituitary | -- | -- | 14,170 | -- | -- | 13,900 |
| Craniopharyngioma | -- | -- | 650 | -- | -- | 660 |
| Unclassified Tumors | 1,430 | 1,830 | 3,260 | 1,440 | 1,730 | 3,180 |
| Hemangioma | -- | -- | 800 | -- | -- | 790 |
| Neoplasm, unspecified | 1,410 | 920 | 2,340 | 1,420 | 840 | 2,260 |
| All other | -- | -- | 130 | -- | -- | 130 |
| TOTAL | 26,670 | 66,800 | 93,470 | 26,940 | 67,440 | 94,390 |
aSource: Estimation based on CBTRUS, NPCR, and SEER 2000-2018 data for malignant tumors, and NPCR and SEER 2006-2018 data for non-malignant tumors.
bRounded to the nearest 10. Numbers may not add up due to rounding.
cTotal estimate is based on overall estimate. Histopathology-specific estimates may not add up to total.
- Estimated number is less than 50 or allows for back-calculation of a value less than 50. These cases are included in overall rates.
Abbreviations: CBTRUS, Central Brain Tumor Registry of the United States; NPCR, National Program of Cancer Registries; SEER, Surveillance, Epidemiology, and End Results Program.