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. Author manuscript; available in PMC: 2023 Oct 1.
Published in final edited form as: J Stroke Cerebrovasc Dis. 2022 Aug 30;31(10):106724. doi: 10.1016/j.jstrokecerebrovasdis.2022.106724

Table 3:

Summary of adverse effects (number of persons with worsened adverse effect from baseline | number of persons with improved adverse effect from baseline)

ADVERSE EFFECT CHECKLIST WEEK 3 WORSENED | IMPROVED FROM BASELINE
Cyproheptadine Placebo
DRY MOUTH 14 | 1 5 | 7
LOW ENERGY 12 | 6 7 | 9
LOW MOTIVATION 11 | 4 4 | 0
WEIGHT GAIN 8 | 4 3 | 8
CONSTIPATION 9 | 3 4 | 5
RESTLESS OR JITTERY 8 | 4 4 | 2
LIGHTHEADEDNESS 8 | 6 5 | 5
FREQUENT URINATION 8 | 8 5 | 11
SLOWNESS/TROUBLE GETTING MOVING 8 | 10 3 | 14
SLEEP PROBLEMS 7 | 12 4 | 6
DROOLING 5 | 4 5 | 3
SHAKING 4 | 3 0 | 8
ANXIETY 4 | 10 1 | 4
NAUSEA 3 | 0 1 | 0
MEMORY PROBLEMS 3 | 5 1 | 10
WEIGHT LOSS 3 | 6 1 | 8
DIFFICULTY URINATING 2 | 2 3 | 1
HEADACHES 2 | 2 2 | 6
DIFICULTY CONCENTRATING 2 | 6 4 | 6
BLURRED VISION 2 | 11 2 | 6
VOMITING 1 | 1 0 | 0
CHANGES IN BREASTS 1 | 1 0 | 0
PROBLEMS WITTH SEXUAL FUNCTION 1 | 2 0 | 2
MUSCLE STIFFNESS 1 | 15 2 | 14
CHANGES IN MENSES 0 | 0 0 | 1
HEART FLUTTERS 0 | 1 1 | 0
FALLS 0 | 6 0 | 1