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. 2022 Oct 5;12:16604. doi: 10.1038/s41598-022-21221-4

Table 2.

Mean 25(OH)D concentrations by population sub-group, stratified by sex.

Adjusteda Mean (95% CI) p-interaction
Female Male
Age group, years
18–29 23.8 (23.2, 24.3) 21.2 (20.2, 22.2)  < 0.001
30–44 25.8 (25.5, 26.1) 23.6 (23.0, 24.2)
45–59 24.4 (24.1, 24.7) 24.1 (23.5, 24.7)
60–74 23.6 (23.3, 23.9) 24.7 (23.8, 25.6)
 ≥ 75 21.1 (20.6, 21.7) 22.1 (20.5, 23.7)
P-trend  < 0.001 0.001
Season
Summer/fall 26.0 (25.7, 26.2) 27.2 (26.6, 27.8)  < 0.001
Winter/spring 23.2 (23.0, 23.4) 21.1 (20.7, 21.6)
P-difference  < 0.001  < 0.001
Year
2013–2014 24.8 (24.4, 25.3) 25.9 (24.9, 26.9)  < 0.001
2015 24.3 (23.8, 24.8) 25.4 (24.3, 26.6)
2016 24.7 (24.3, 25.1) 25.3 (24.4, 26.3)
2017 24.3 (24.0, 24.5) 24.3 (23.6, 25.1)
2018 23.9 (23.6, 24.2) 21.0 (20.5, 21.6)
P-trend 0.001  < 0.001
Federal district
Central 24.7 (24.4, 24.9) 24.2 (23.7, 24.8)  < 0.001
Far Eastern 27.2 (26.4, 28.0) 29.0 (27.1, 30.9)
North Caucasian 19.0 (18.3, 19.8) 22.1 (20.2, 24.0)
Northwestern 24.4 (23.9, 24.8) 19.2 (18.5, 19.8)
Siberian 24.4 (24.0, 24.8) 25.1 (23.9, 26.2)
South 23.8 (23.1, 24.5) 27.1 (25.4, 28.8)
Ural 25.3 (24.6, 26) 26.1 (24.2, 27.9)
Volga 23.2 (22.6, 23.8) 26.2 (24.8, 27.6)
P-difference  < 0.001  < 0.001

Data are from 2013 to 2018 and are from all months of the year. a Values represent age group, season, year of data collection and federal district adjusted means estimated via marginal values following the fitting of a linear regression model.