Fig. 3. Self-healing mechanism of chemically fueled Fmoc-AAD-OH in a pseudo-steady-state. (A) Schematic depiction of the proposed self-healing mechanism. (B) Critical aggregation concentration of molecular glue and self-healing (rheological) at t = 5 minutes of Fmoc-AAD-OH, Fmoc-AVD-OH, and ac-FIID-OH. (C) Cryo-TEM micrographs of 10 mM Fmoc-AAD-OH fueled with 10 mM EDC without ultrasonication at t = 1 minute after fuel addition (undamaged), ultrasonication at t = 1 minute after fuel addition (damaged), 25 min after ultrasonication at 1 minute after fuel addition (healed). (D) Ratio of the number of end caps over the number of fibers per 1 μm2 at t = 1 minute after fuel addition without damaging (undamaged), damaging at t = 1 minute after fuel addition (damaged), 25 min after damaging at t = 1 min after fuel addition (healed). All experiments were performed in triplicate.
