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. 2022 Oct 3;21:200. doi: 10.1186/s12933-022-01634-1

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 5 — Pearson correlation analysis of the correlation between changes in EPCs and baPWV (ΔEPCs and baPWV) and changes in other clinical parameters (r). a MET group; b MET-DUL group. BMI body mass index, SBP systolic pressure, DBP diastolic pressure, FPG fasting plasma glucose, FCP fasting C peptide, HbA1c, glycated haemoglobin A1c, TG triglyceride, TCH total cholesterol, HDL-C high density lipoprotein cholesterol, LDL-C low density lipoprotein cholesterol, NO nitric oxide, VEGF vascular endothelial growth factor, SDF-1α stromal cell derived factor-1α, CRP C-reactive protein; TNF-α tumour necrosis factor-α, IL-6 interleukin-6, AGEs advanced glycation end products, EPCs endothelial progenitor cells, baPWV brachial–ankle pulse wave velocity, EPA proliferative ability of endothelial progenitor cells, EAA adhesion ability of endothelial progenitor cells, EMA migration ability of endothelial progenitor cells, ETF tubule forming ability of endothelial progenitor cells; ∆ the change value of various index before and after treatment; r correlation coefficient